Protein Info for MPMX19_02587 in Azospirillum sp. SherDot2

Annotation: Phosphate regulon transcriptional regulatory protein PhoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 TIGR02154: phosphate regulon transcriptional regulatory protein PhoB" amino acids 22 to 244 (223 residues), 342.8 bits, see alignment E=3.6e-107 PF00072: Response_reg" amino acids 23 to 134 (112 residues), 109.6 bits, see alignment E=9.6e-36 PF00486: Trans_reg_C" amino acids 168 to 243 (76 residues), 95.2 bits, see alignment E=2e-31

Best Hits

Swiss-Prot: 57% identical to PHOB_RHIME: Phosphate regulon transcriptional regulatory protein PhoB (phoB) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K07657, two-component system, OmpR family, phosphate regulon response regulator PhoB (inferred from 99% identity to azl:AZL_000280)

Predicted SEED Role

"Phosphate regulon transcriptional regulatory protein PhoB (SphR)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (248 amino acids)

>MPMX19_02587 Phosphate regulon transcriptional regulatory protein PhoB (Azospirillum sp. SherDot2)
MPVNVETRAVNGATMNAALKPLVLIVEDEADILTLLKYNLEKEGFRVATASDGEEALLAA
GEQTPHIVLLDWMLPLMSGLEVCRQLRRNAKTRDIPIIMLTARGEEGDRVRGLNSGADDY
ITKPFSPTELVARMRAVLRRASPGMTDEVLTFADVTMDLAAHRVRRNGRDVHLGPTEFRL
LRHFMQHAGRVFSREQLLDLVWGHDVYVEPRTVDVHIRRLRKAMNEEDELDLIRTVRSAG
YALDTKSM