Protein Info for MPMX19_02559 in Azospirillum sp. SherDot2

Annotation: 7-methyl-GTP pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 201 transmembrane" amino acids 178 to 195 (18 residues), see Phobius details PF02545: Maf" amino acids 6 to 194 (189 residues), 142.1 bits, see alignment E=8.6e-46

Best Hits

Swiss-Prot: 66% identical to NTPP_MAGSA: Nucleoside triphosphate pyrophosphatase (amb4548) from Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)

KEGG orthology group: K06287, septum formation protein (inferred from 92% identity to azl:AZL_000020)

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (201 amino acids)

>MPMX19_02559 7-methyl-GTP pyrophosphatase (Azospirillum sp. SherDot2)
MSAAPKLVLASGSRTRAAMLEQAGVTAILDRPLVDEDEVKAAGRAEGVPADAVAEALAEL
KAQRITRRHPGALVVGADQMLDCEGRWFDKPADRAAARAQLLDLRGKTHQLVSCAVVVRD
GERMWHKTDSARLTMRNFSEAFLDDYLDRVGDEVLHSVGAYQLEGLGAQLFHRVEGDFFT
ILGLPLLPLLGFLRVHGVGRE