Protein Info for MPMX19_02465 in Azospirillum sp. SherDot2

Annotation: Aspartate/alanine antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 559 transmembrane" amino acids 14 to 32 (19 residues), see Phobius details amino acids 39 to 57 (19 residues), see Phobius details amino acids 77 to 96 (20 residues), see Phobius details amino acids 104 to 127 (24 residues), see Phobius details amino acids 165 to 191 (27 residues), see Phobius details amino acids 382 to 401 (20 residues), see Phobius details amino acids 413 to 435 (23 residues), see Phobius details amino acids 444 to 464 (21 residues), see Phobius details amino acids 474 to 494 (21 residues), see Phobius details amino acids 502 to 522 (21 residues), see Phobius details amino acids 534 to 558 (25 residues), see Phobius details PF06826: Asp-Al_Ex" amino acids 21 to 188 (168 residues), 118 bits, see alignment E=3.9e-38 amino acids 384 to 555 (172 residues), 156.7 bits, see alignment E=5.2e-50 TIGR01625: AspT/YidE/YbjL antiporter duplication domain" amino acids 27 to 176 (150 residues), 103.3 bits, see alignment E=5.4e-34 amino acids 388 to 542 (155 residues), 141.2 bits, see alignment E=1.2e-45 PF02080: TrkA_C" amino acids 303 to 370 (68 residues), 46.8 bits, see alignment E=2.3e-16

Best Hits

Swiss-Prot: 54% identical to Y3727_YERPN: Putative transport protein YPN_3727 (YPN_3727) from Yersinia pestis bv. Antiqua (strain Nepal516)

KEGG orthology group: K07085, putative transport protein (inferred from 95% identity to azl:AZL_028000)

Predicted SEED Role

"Mediator of hyperadherence YidE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (559 amino acids)

>MPMX19_02465 Aspartate/alanine antiporter (Azospirillum sp. SherDot2)
MSAFADILQAMPPIARVVFMLGLVSAAGVALGHIKIRGVGLGIGGVLFSGIAGGHIAKQA
GIAFNLEMMDFIRDFGLILFVYTIGIQVGPGFFAALRRTGLALNGLALLMVGSSILLTAV
LVSSGALSLGSSLGVFAGAVTNAPALAATQQVLTEVGADAAVMALPGLAFAVTYPFGIAG
NLLSMAAVRILFRIDPEAEATRFEDCRRAEVSTLETMDLAVRNPELAGRPLGSIDLLCGQ
GVVASRLLCDGKLCVPHDGTCLKLGDVLHVVGPRPKLEQVRALLGQEFDRPLTTKGTDLK
WERIVVTNNAVLGKSIATLNLQDAHDVVVSRVNRSGVELVPTPALKLQFGDILTVIGRPD
SLAAVGQIFGNSTRKLQQVEMIPMFLGIALGAALGAIPIFLPGMPAPLRLGLAGGPLIVA
LILGRIGHVGPLVWFMPPAANLALREIGIILFLAVLGIASGDRFVATLASGAGWPWMIWG
VLVTLVPLLLTGLVARGLMKLNFLTICGVLAGAQTNPPGLAYANALVASEAPALAYATVY
PLAMCLRILGPQILVLLLW