Protein Info for MPMX19_02421 in Azospirillum sp. SherDot2

Annotation: putative signaling protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 581 TIGR00229: PAS domain S-box protein" amino acids 26 to 144 (119 residues), 51.5 bits, see alignment E=1.1e-17 PF00989: PAS" amino acids 27 to 135 (109 residues), 28.7 bits, see alignment E=2.9e-10 PF13596: PAS_10" amino acids 28 to 136 (109 residues), 23.2 bits, see alignment E=2.3e-08 PF08448: PAS_4" amino acids 32 to 140 (109 residues), 60.2 bits, see alignment E=5.5e-20 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 147 to 302 (156 residues), 54.5 bits, see alignment E=1.2e-18 PF00990: GGDEF" amino acids 149 to 301 (153 residues), 76.9 bits, see alignment E=4.1e-25 PF00563: EAL" amino acids 323 to 561 (239 residues), 261 bits, see alignment E=2.4e-81

Best Hits

KEGG orthology group: None (inferred from 90% identity to azl:AZL_001630)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (581 amino acids)

>MPMX19_02421 putative signaling protein (Azospirillum sp. SherDot2)
MSPDPRITALADALSGATSGAPGLDALRQILDAMTVKVALMDPQRRHIYANRAYLEMMGT
TLEKAVGTTIGDLLGPDLLRNTVGAAKRALAGETVQTEGWITQADGQQRYVTRLHAPHRA
EDGAIAGYFVILQDMTERRQVQDDLFRLAYYDPVTGLANRLMLLKHMADYRNMGEPFTLV
ILDIDRFAEIRSSMGQGFANEVLDGLAQRMAAQAAAFDLIARVSDHAFAMLAGGACDRPV
LEGAIEELASVVRSARSSSGGTVFLSASIGVAIAAPTHERPDDVLRDAEIATARAREQGG
GRQAWFDPAMHSHVVEQVRLEHDLRSALDSGSDLWVAYQPIVEMVTGGLAGFEALMRWNH
PERGNIPPGIFIPIAESTGLVVSLGTWVLRQACLQIAEWQDRREPGSAPLFMSVNLSTHQ
LSDPNFVQVVREVLRETGVEPSWIKLELTESAVMDKAEQSIRLLRDLRALGIKLSIDDFG
TGYSSLSYLHKLPIDSLKVDRSFVSAMHQSEENRAIVRIIMDLARLLGFDVIAEGIETSA
DANLLRALACDYGQGYHFARPLPSADAGKLVGGDLPWQMPR