Protein Info for MPMX19_02418 in Azospirillum sp. SherDot2

Annotation: Disulfide-bond oxidoreductase YfcG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 211 transmembrane" amino acids 157 to 179 (23 residues), see Phobius details PF02798: GST_N" amino acids 2 to 78 (77 residues), 41.6 bits, see alignment E=3.9e-14 PF13417: GST_N_3" amino acids 4 to 81 (78 residues), 37.8 bits, see alignment E=5.9e-13 PF13409: GST_N_2" amino acids 10 to 79 (70 residues), 40.5 bits, see alignment E=1e-13 PF13410: GST_C_2" amino acids 126 to 190 (65 residues), 45.6 bits, see alignment E=1.9e-15 PF14497: GST_C_3" amino acids 130 to 199 (70 residues), 34.3 bits, see alignment E=6.8e-12 PF00043: GST_C" amino acids 132 to 196 (65 residues), 46.2 bits, see alignment E=1.3e-15

Best Hits

Swiss-Prot: 44% identical to YFCG_ECOLI: Disulfide-bond oxidoreductase YfcG (yfcG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 93% identity to azl:AZL_001660)

MetaCyc: 44% identical to disulfide bond oxidoreductase YfcG (Escherichia coli K-12 substr. MG1655)
RXN0-6256

Predicted SEED Role

"Glutathione S-transferase (EC 2.5.1.18)" in subsystem Glutathione: Non-redox reactions (EC 2.5.1.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.18

Use Curated BLAST to search for 2.5.1.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (211 amino acids)

>MPMX19_02418 Disulfide-bond oxidoreductase YfcG (Azospirillum sp. SherDot2)
MLTLYSFPTPNGRKASILLEELGLPYTVHRVDLAAGENKRPDFLAVSPITKIPALAEELP
GGRVRRLFGSGAILLHFAERTGRLLPEDEDERAEAMSWFMLGISDLGPTAIDMQRFAARS
PDRIPHAIDLYKGELMRCYAALEERLGTAEHLAGASYSIADIACFPFIAAAAVAGGGLLE
RFPNLKRWHDTVAARPAVQRGMAVPDLAASG