Protein Info for MPMX19_02224 in Azospirillum sp. SherDot2

Annotation: Glucose-1-phosphate adenylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR02091: glucose-1-phosphate adenylyltransferase" amino acids 15 to 392 (378 residues), 517.4 bits, see alignment E=1e-159 PF00483: NTP_transferase" amino acids 16 to 285 (270 residues), 215.8 bits, see alignment E=1.1e-67 PF12804: NTP_transf_3" amino acids 16 to 166 (151 residues), 31.2 bits, see alignment E=3.7e-11 PF24894: Hexapep_GlmU" amino acids 309 to 412 (104 residues), 148.5 bits, see alignment E=9.3e-48

Best Hits

Swiss-Prot: 67% identical to GLGC_SINFN: Glucose-1-phosphate adenylyltransferase (glgC) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K00975, glucose-1-phosphate adenylyltransferase [EC: 2.7.7.27] (inferred from 98% identity to azl:AZL_003050)

MetaCyc: 60% identical to glucose-1-phosphate adenylyltransferase (Escherichia coli K-12 substr. MG1655)
Glucose-1-phosphate adenylyltransferase. [EC: 2.7.7.27]

Predicted SEED Role

"Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)" in subsystem Glycogen metabolism (EC 2.7.7.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>MPMX19_02224 Glucose-1-phosphate adenylyltransferase (Azospirillum sp. SherDot2)
MLDKRDLRLAPRRAVALVLAGGRGSRLKQLTDRRAKPATYFGGKYRIIDFALSNCVNSGF
RRIGVLTQYKSHSLLRHLQRGWNVFRGEMNEFCDLLPAQQRVSETEWYQGTADAVFQNLD
ILRDHEPEYVLILAGDHIYKMDYGALLLDHIDRKADVTVPCIAVPREQASGFGVMHIDEE
RRIIDFVEKPADPPPMPGRPDMALASMGIYVFNAQFLYDQLERDVATPGSSRDFGKDIIP
HLVKTGARIIAHDYADSAIIDAPDDAPYWRDVGTIDAYWEANLDLCHVTPQLNMYNRDWP
IFTYQEQLPPAKFVFDDENRRGTAIDSLVSGGCIISGSTVRRSLLFSSVRVNSYSELHEA
VVLPECDIGRHCRLKKVVIDRGVSIPNGLVVGEDAELDARRFHRSEGGVVLITREMIEKL
PKE