Protein Info for MPMX19_02193 in Azospirillum sp. SherDot2

Annotation: Holliday junction ATP-dependent DNA helicase RuvB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 620 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 20 to 380 (361 residues), 425.4 bits, see alignment E=1e-131 PF13177: DNA_pol3_delta2" amino acids 38 to 200 (163 residues), 133.3 bits, see alignment E=3.5e-42 PF13401: AAA_22" amino acids 56 to 179 (124 residues), 27.3 bits, see alignment E=1.6e-09 PF00004: AAA" amino acids 59 to 194 (136 residues), 38.6 bits, see alignment E=5.7e-13 PF12169: DNA_pol3_gamma3" amino acids 254 to 395 (142 residues), 177.9 bits, see alignment E=3.9e-56 PF12362: DUF3646" amino acids 465 to 578 (114 residues), 124.4 bits, see alignment E=1.1e-39

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 91% identity to azl:AZL_025120)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (620 amino acids)

>MPMX19_02193 Holliday junction ATP-dependent DNA helicase RuvB (Azospirillum sp. SherDot2)
MTDTTAEITAASAPATGQAYRVLARKYRPKTFDELIGQDALVRTLTNAIQSGRIAQAFML
TGVRGVGKTTTARIIARALNCTGPDGTGGPTVSPCGVCDNCRAIAEDRHVDVMEMDAASH
TGVDDIREIIDGVRYSPVSARYKLYIIDEVHMLSKSAFNALLKTLEEPPSHVKFVFATTE
IRKVPVTVLSRCQRFDLRRVDAQVLKEHFTRVTAMEGAGIEGDATSLIARAADGSVRDGL
SLLDQAIALAAGTVTAQQVRDMLGLADRTRVIDLFEAAVSAKPAEAMDILADLHRVGADP
VVILQDLLDLVHNLTRLKVVPDSANDPSLPEAERTRGASLSSKLGMPALTRAWQLLLKGL
NEVQAAPVPQQALEMVIVRLSYAADLPTPGELIRQFQAQQANGGGGGAPMGRGPGGGGGP
VAVATQSTHAVARSMGSAQPQSAAVAQAAPAPAAIPEGEELSPMPHDFRALVQLFSDRRE
GALYGYMMETVQLVRMEPGTLELKLRPAAPPTLPAKVGQFLTEWTGQRWIVALSEGPAQP
TLAEQDKAEKHRAWAEAEANPVVRAVLDAFSGAKIIDIRDLAEVAAAESAAVADDGETPD
FMVQQQDDGVYYPLDDEGEY