Protein Info for MPMX19_02046 in Azospirillum sp. SherDot2

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1034 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 279 to 301 (23 residues), see Phobius details PF02743: dCache_1" amino acids 65 to 247 (183 residues), 54.1 bits, see alignment E=7.6e-18 PF17203: sCache_3_2" amino acids 96 to 180 (85 residues), 30 bits, see alignment E=2.3e-10 PF00672: HAMP" amino acids 301 to 349 (49 residues), 27.1 bits, see alignment 2e-09 TIGR00229: PAS domain S-box protein" amino acids 355 to 488 (134 residues), 47.3 bits, see alignment E=1.1e-16 amino acids 503 to 611 (109 residues), 32.8 bits, see alignment E=3.4e-12 PF00989: PAS" amino acids 360 to 478 (119 residues), 29.2 bits, see alignment E=3.6e-10 PF08448: PAS_4" amino acids 365 to 483 (119 residues), 52.6 bits, see alignment E=2.3e-17 amino acids 503 to 605 (103 residues), 57.6 bits, see alignment E=6.2e-19 PF13426: PAS_9" amino acids 374 to 480 (107 residues), 34.6 bits, see alignment E=8.7e-12 amino acids 518 to 603 (86 residues), 22.7 bits, see alignment E=4.5e-08 PF00512: HisKA" amino acids 625 to 689 (65 residues), 41.8 bits, see alignment 4.2e-14 PF02518: HATPase_c" amino acids 734 to 839 (106 residues), 83.3 bits, see alignment E=7.8e-27 PF00072: Response_reg" amino acids 916 to 1027 (112 residues), 45.3 bits, see alignment E=4.1e-15

Best Hits

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1034 amino acids)

>MPMX19_02046 Sensor histidine kinase RcsC (Azospirillum sp. SherDot2)
MTLLARLFILVLLAVLPAIGIQIYSVLEQRAEREGEVTLQAERLLRQVESEHFRLIDSAR
LMVTAVTEARFLRRGEIDNCQSYLERLATRSADYRTLSITDTEGRILCSADPSRIGASLS
VQPHFRRAMTQGRFAVGEWTITHSGADGGELPVAAPYSDSNGRRAGVVALSLDVPRLTAL
FASRPMPDNTTLTVADRSGTILVKLPGTQGRSGERLPDSYLGLLSEREAGVTMLPGLDGV
SRILAFSPPSAGIRDLFISIGVDRGAAMGAVDRATRDGLLMTLSGFLVAAAAAWIGGTLF
IRRPVDALVSAARDWSEGKTATRVKLSDRSSEIGQLGYAFDMMAERLEAREAALRQSESH
IRAVLDALPAYVGVLTPDGAVAQVNRAAADAAGLPPARIVGRPFDEICWLSFDEAGRERL
RQALALGAGGRSSRFDAGLRVATGRDTAPREMTVDVNLTPMVDADGHVTHLIATGIDITE
RKRTEEALRVAEERVRTGLRNSGVVVLNQDRDLRYTWAHSEWLGFSPDALIGRTDADLCS
QREDADGMMALKRRVMESGVGAREEVRIRCKGEDRFFDLTIDPLLDPSGRVEGVTCAAVE
VTDRKKAEAELRRAREEADQANDGKSKFLAAASHDLRQPVQSLYLFTAALSDRLQGHAAL
PILDNIRQGLDTLKSLLDGLLDMSRLESGKIVATPVEVRLNQMLGRLVAEYGPRAAQKGL
ELRAVPTRAWVRTDPAHLERILRNLVENALRYTTRGKVLLGCRRTPSGMRVEVWDTGAGI
PADRLEDIFEEFTQLGERSERGLGLGLAIVKRLSRLLGHPVTVRSWEGKGSVFAVELPRV
ILGNPRPASGTAAAAATLARRSVANDAAAANDRGQAISAIANAFGGGRSAGGTTKTIAAP
AAVATGAGAGAAKGMVLVIDDEAIILLGLKAILEGWGYDVLTAKSGDQALERLRADGRCP
QIVLADYQLQQGRTGPEAVCAVQTMLGQSVPGIILTGDTSSERQEEAERRGFRILHKPVF
PNDLRRMMASAGAA