Protein Info for MPMX19_02013 in Azospirillum sp. SherDot2

Annotation: Biosynthetic peptidoglycan transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details TIGR02070: monofunctional biosynthetic peptidoglycan transglycosylase" amino acids 15 to 216 (202 residues), 266.7 bits, see alignment E=7.5e-84 PF00912: Transgly" amino acids 45 to 211 (167 residues), 175.5 bits, see alignment E=3.6e-56

Best Hits

Swiss-Prot: 60% identical to MTGA_RHOCS: Biosynthetic peptidoglycan transglycosylase (mtgA) from Rhodospirillum centenum (strain ATCC 51521 / SW)

KEGG orthology group: K03814, monofunctional biosynthetic peptidoglycan transglycosylase [EC: 2.4.1.-] (inferred from 89% identity to azl:AZL_024110)

Predicted SEED Role

"Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-)" in subsystem Peptidoglycan Biosynthesis (EC 2.4.2.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.-, 2.4.2.-

Use Curated BLAST to search for 2.4.1.- or 2.4.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (224 amino acids)

>MPMX19_02013 Biosynthetic peptidoglycan transglycosylase (Azospirillum sp. SherDot2)
MRKLLRWALIGIAGLMAFTILWAALYRVVPPPATPLMLIRALGGSGLSRDWEPLERISPA
LVEAVIASEDTGFCGHGGFDWAAIEGAFEENEEGRRLRGGSTISQQTAKNAFLWPDRSWT
RKGAEAWFTLLIESLWSKRRILEVYLNIVEWDDGVYGAEAAARHHFNKSAAALTRREAAL
LAVVLPSPRNWSPTKPSAYVARRAGVIERRMAVVRRDGLADCVR