Protein Info for MPMX19_01820 in Azospirillum sp. SherDot2

Annotation: Inner membrane protein YohK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 240 transmembrane" amino acids 13 to 34 (22 residues), see Phobius details amino acids 42 to 62 (21 residues), see Phobius details amino acids 73 to 90 (18 residues), see Phobius details amino acids 101 to 125 (25 residues), see Phobius details amino acids 158 to 180 (23 residues), see Phobius details amino acids 212 to 238 (27 residues), see Phobius details PF04172: LrgB" amino acids 23 to 236 (214 residues), 274.9 bits, see alignment E=2e-86

Best Hits

Swiss-Prot: 41% identical to YOHK_ECOLI: Inner membrane protein YohK (yohK) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 90% identity to azl:AZL_022290)

Predicted SEED Role

"LrgA-associated membrane protein LrgB" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (240 amino acids)

>MPMX19_01820 Inner membrane protein YohK (Azospirillum sp. SherDot2)
MSADLHQIWVYLSANPLAGLTLTLVAYQIGLWVFEKLGRRPVLNPVLIAVVLIAGTLSLS
GIDYRTYFDGAQFVHFLLGPATVALAIPLYNQFQEVRRSAVALVVALLVGSAASALSAVA
LVWAFGGSKATILSMAPKSVTSPIAMGVSEQIGGLPSLTAVFVIITGIVAASLGTWVLNL
VRVKDWRARGFGMGVAAHGIGTARALQVNEVAGAFAGLGMGLNGLATALLLPTLYHLIWG