Protein Info for MPMX19_01812 in Azospirillum sp. SherDot2

Annotation: Ribonuclease R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 716 TIGR02063: ribonuclease R" amino acids 7 to 714 (708 residues), 695.9 bits, see alignment E=6.3e-213 TIGR00358: VacB and RNase II family 3'-5' exoribonucleases" amino acids 121 to 704 (584 residues), 495.4 bits, see alignment E=2.4e-152 PF17876: CSD2" amino acids 166 to 237 (72 residues), 45.7 bits, see alignment E=8.2e-16 PF00773: RNB" amino acids 255 to 584 (330 residues), 333.8 bits, see alignment E=1.8e-103 PF00575: S1" amino acids 632 to 704 (73 residues), 40.9 bits, see alignment E=3.4e-14

Best Hits

KEGG orthology group: K12573, ribonuclease R [EC: 3.1.-.-] (inferred from 93% identity to azl:AZL_022230)

Predicted SEED Role

"3'-to-5' exoribonuclease RNase R" in subsystem RNA processing and degradation, bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (716 amino acids)

>MPMX19_01812 Ribonuclease R (Azospirillum sp. SherDot2)
MTDSHFPSKDAILAFIRSSTTPVGKREIARAFKLSGSADRETLKDLLRELEADGTVERGR
NKRMAPPQALPAVAVLLVTGADADGELAARPLTWTGEGNPPRIFLLPEKKSRGEEKPLAV
GDTLLAKLARINDRLYEARVIRRIDGEREGRILGVYRPSADGGRILPTDRRHKTEFLVLP
PNRGDAEPGDLVFADILPAGRAGQPQARVVERLGSTDEPRAFSLIAIHAHGIPTVFPHAA
LREAELAAVPAQMQREDLRDIPLVTIDGADARDFDDAVWAEADGDPENPDGWHLIVAIAD
VSYYVRPGSALDRTAYERGNSVYFPDRVVPMLPEALSNGLCSLRPGEDRACLAFHLWIDR
SGVLIRHRLVRGLMRSVARLIYEQVQDCHDGRPDEVTGPLADGVIAPLFGAYARLAAARA
KRGTLELDLPERRVHIDERGRVAEIVRRERHDSHRLIEEFMIAANVAAAEVLERRTMPGL
YRIHDRPSMEKMEALRGFLAGIGHPLTKSADLTPDHFTRILRKVEGTSHATLVSEVVLRA
QAQAAYSPDNIGHFGLALHRYAHFTSPIRRYADLIVHRALIRTLGLGVGGLDDETLGRLA
EIGDHLSSTERRAATAERDAVDRYTAAFLADRIGDRFSGRISGVSRFGLFVRLDESGADG
LVPASSLPDDRYDHDEAAHALVGQRTGRTYRLSSPVKVVLVEADPVSGSTLFRLAD