Protein Info for MPMX19_01738 in Azospirillum sp. SherDot2

Annotation: NADH-quinone oxidoreductase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01971: NADH-quinone oxidoreductase, chain I
  • amino acids 19 to 140 (122 residues), 170.6 bits, E=4.8e-55
• PF00037: Fer4
  • amino acids 60 to 79 (20 residues), 24.2 bits, see alignment (E = 1.2e-08)
  • amino acids 96 to 117 (22 residues), 33.7 bits, see alignment (E = 1.2e-11)
• PF13237: Fer4_10
  • amino acids 60 to 113 (54 residues), 29.4 bits, E=3.7e-10
• PF12800: Fer4_4
  • amino acids 61 to 75 (15 residues), 17.8 bits, see alignment (E = 1.9e-06)
  • amino acids 100 to 114 (15 residues), 14.8 bits, see alignment (E = 1.7e-05)
• PF13183: Fer4_8
  • amino acids 61 to 114 (54 residues), 28.7 bits, E=8.7e-10
• PF12838: Fer4_7
  • amino acids 62 to 116 (55 residues), 47.7 bits, E=9.3e-16
• PF13187: Fer4_9
  • amino acids 62 to 116 (55 residues), 32.7 bits, E=3.5e-11

Best Hits

Swiss-Prot: 80% identical to NUOI_MAGSA: NADH-quinone oxidoreductase subunit I (nuoI) from Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)

KEGG orthology group: K00338, NADH dehydrogenase I subunit I [EC: 1.6.5.3] (inferred from 97% identity to azl:AZL_021400)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

• aerobic respiration III (alternative oxidase pathway) (3/3 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (1/2 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Protein Sequence (162 amino acids)

>MPMX19_01738 NADH-quinone oxidoreductase subunit I (Azospirillum sp. SherDot2)
MAFLDRAARSLFLTELLGGMALTLRYMFKPKVTLNYPYEKGPISSRFRGEHVLRRYASGE
ERCIACKLCEAVCPALAITIEAEPRDDGSRRTTRYDIDMTKCIYCGLCQEACPVDAVVMG
PNFEFSTESREELFYNKQKLLANGDRWEAEIAQNLAAEAPYR