Protein Info for MPMX19_01608 in Azospirillum sp. SherDot2

Annotation: Release factor glutamine methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 PF06325: PrmA" amino acids 63 to 296 (234 residues), 165.5 bits, see alignment E=5.2e-52 PF05175: MTS" amino acids 154 to 217 (64 residues), 33.9 bits, see alignment E=6.4e-12 PF13489: Methyltransf_23" amino acids 159 to 266 (108 residues), 29.7 bits, see alignment E=1.3e-10 PF13649: Methyltransf_25" amino acids 161 to 254 (94 residues), 37.3 bits, see alignment E=9.4e-13 PF08241: Methyltransf_11" amino acids 161 to 257 (97 residues), 25.4 bits, see alignment E=4.5e-09

Best Hits

Swiss-Prot: 44% identical to PRMA_CHESB: Ribosomal protein L11 methyltransferase (prmA) from Chelativorans sp. (strain BNC1)

KEGG orthology group: K02687, ribosomal protein L11 methyltransferase [EC: 2.1.1.-] (inferred from 99% identity to azl:AZL_019650)

Predicted SEED Role

"Ribosomal protein L11 methyltransferase (EC 2.1.1.-)" in subsystem Heat shock dnaK gene cluster extended or Ribosome biogenesis bacterial (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (296 amino acids)

>MPMX19_01608 Release factor glutamine methyltransferase (Azospirillum sp. SherDot2)
MSQTPLWRIALVVPEAHAPAFAEAVGDHADAVSTFELEEGGNWLVEATLYGAPDEARLQS
RVAVLAKALGIEEPRLAVENLPPIDWVSHSYQGFPPIRAGRFFVHGSHHEGIVPAGSIPL
LVDAATAFGTGEHGSTNGCLQALDRLSRHLKLPRGGKRGALDMGCGSGILALAVAKRWRV
PVTAVDIDPEAVRVTRINAALNGQKGMIRAQGGDGYHTRIVGRHKPYTLITANILARPLS
RMAPQLRRHLKKGGYAVLAGLLNRQERHVIQAHRNQGLRLVARIPVGEWTTLVVKR