Protein Info for MPMX19_01597 in Azospirillum sp. SherDot2

Annotation: 23S rRNA (uridine(2479)-2'-O)-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 PF00588: SpoU_methylase" amino acids 118 to 246 (129 residues), 83.5 bits, see alignment E=8.3e-28

Best Hits

KEGG orthology group: K03437, RNA methyltransferase, TrmH family (inferred from 93% identity to azl:AZL_019530)

Predicted SEED Role

"SpoU rRNA Methylase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (254 amino acids)

>MPMX19_01597 23S rRNA (uridine(2479)-2'-O)-methyltransferase (Azospirillum sp. SherDot2)
MTRPPLLIESPQNPQFKLWESALESRGLKKNGKFLLAGLKTVPEALRQHPERFERLLFTD
PAQISSWRLPPGVEPVQLAPALFRMLDVSGTGFPLLVGAVPKMPAIDLSQPPQGLELLCA
LGDPSNLGALLRSAAAFGVSRVVLLEGAAHPFHPKCLRAASNAQFTLTLLRGPRWTAVNE
AAGPLYALDGGGEDLTRFDWPADMRLILGEEGQGVPADCPATRLSVPTTGAVESLNATVA
VSVALFARYAAVKG