Protein Info for MPMX19_01578 in Azospirillum sp. SherDot2

Annotation: Peptide deformylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 178 PF01327: Pep_deformylase" amino acids 2 to 150 (149 residues), 165.3 bits, see alignment E=4.2e-53 TIGR00079: peptide deformylase" amino acids 2 to 157 (156 residues), 129.7 bits, see alignment E=3.8e-42

Best Hits

Swiss-Prot: 45% identical to DEF_CHLTA: Peptide deformylase (def) from Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13)

KEGG orthology group: K01462, peptide deformylase [EC: 3.5.1.88] (inferred from 87% identity to azl:AZL_019350)

Predicted SEED Role

"Peptide deformylase (EC 3.5.1.88)" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase (EC 3.5.1.88)

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.88

Use Curated BLAST to search for 3.5.1.88

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (178 amino acids)

>MPMX19_01578 Peptide deformylase (Azospirillum sp. SherDot2)
MGNPVLRKIAEPIADPTDPAVARLAADMIATMLDAPGVGLAAPQISEPRRIVVFRVPADR
GEGEEVANTVLVNPVIEPLTDEKVLGWEGCLSIPGLRGLVPRYKRIRYRGYGLDGARIER
EASGFHARVVQHEVDHLDGVLYLDRMDDLQLLVCTEEMHHLNAALAAATRDTDAPSRT