Protein Info for MPMX19_01549 in Azospirillum sp. SherDot2

Annotation: Trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 PF05697: Trigger_N" amino acids 1 to 144 (144 residues), 138 bits, see alignment E=4.5e-44 TIGR00115: trigger factor" amino acids 11 to 418 (408 residues), 424.1 bits, see alignment E=2.7e-131 PF00254: FKBP_C" amino acids 157 to 239 (83 residues), 55.9 bits, see alignment E=6.9e-19 PF05698: Trigger_C" amino acids 262 to 418 (157 residues), 123.7 bits, see alignment E=1.1e-39

Best Hits

Swiss-Prot: 58% identical to TIG_RHOCS: Trigger factor (tig) from Rhodospirillum centenum (strain ATCC 51521 / SW)

KEGG orthology group: K03545, trigger factor (inferred from 94% identity to azl:AZL_019180)

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (447 amino acids)

>MPMX19_01549 Trigger factor (Azospirillum sp. SherDot2)
MNITETSTDGLKREFQVVISAKDIEEKVNGKLEELRRTVQLPGFRPGKVPVTVIKQRYFG
GVLSEVLEDAISDSSRQALSERGLRVALQPKIEVEKYEDGGDLTYKMAVELLPDVEPGEF
TGLELEKPVAEVSEEAVNEAVTRLASAHSTQAPVTEDRAAETGDIAVIDFAGTVDGEALE
GMDGKDYPLELGAGRFVPGFEEQLVGVKAGEHRTVNVTFPEDYPHERLKGAATVFEVDVK
ELRKNVPAEVNDELAKEFGMESLEKMREAIRDRIKGEYDGLSRLRVKRQLLDKLAEAHSF
EVPAGMVDIEFEGIWARLQEELKNGTAGEDADKPEDELKAEYRSIAERRVRLGLLLSEVG
RRNNIQVTQDEVNRALINEARRFPGQERQVFEFFKQNQQALENLRAPIFEDKVVDHILDQ
AKVTEKTVSVEELTKDEDEAGNESAAA