Protein Info for MPMX19_01523 in Azospirillum sp. SherDot2

Annotation: Polar-differentiation response regulator DivK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 135 PF00072: Response_reg" amino acids 19 to 130 (112 residues), 88.9 bits, see alignment E=1.3e-29

Best Hits

Swiss-Prot: 75% identical to DIVK_BRUA2: Polar-differentiation response regulator DivK (divK) from Brucella abortus (strain 2308)

KEGG orthology group: K11443, two-component system, cell cycle response regulator DivK (inferred from 96% identity to azl:AZL_018690)

Predicted SEED Role

"Chemotaxis protein CheV (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (135 amino acids)

>MPMX19_01523 Polar-differentiation response regulator DivK (Azospirillum sp. SherDot2)
MPAEPCGPLETGGKPTKTVLIVEDNELNMKLFHDLLEAHGYGTLQTREGMEAMRLARLHR
PDLILMDIQLPEVSGLEVTRWIKDDPELKSIPVVAVTAFAMKGDEEKIRQGGCEDYVAKP
ISVVKFLETVKKFLG