Protein Info for MPMX19_01522 in Azospirillum sp. SherDot2

Annotation: Response regulator PleD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 PF00072: Response_reg" amino acids 5 to 116 (112 residues), 101.1 bits, see alignment E=4.1e-33 amino acids 158 to 269 (112 residues), 63.8 bits, see alignment E=1.6e-21 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 292 to 454 (163 residues), 179.6 bits, see alignment E=2e-57 PF00990: GGDEF" amino acids 293 to 451 (159 residues), 169.7 bits, see alignment E=4.4e-54

Best Hits

Swiss-Prot: 51% identical to PLED_CAUVN: Response regulator PleD (pleD) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K02488, two-component system, cell cycle response regulator (inferred from 96% identity to azl:AZL_018680)

Predicted SEED Role

"Pole remodelling regulatory diguanylate cyclase" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (464 amino acids)

>MPMX19_01522 Response regulator PleD (Azospirillum sp. SherDot2)
MSARVLVVDDVLPNVKLLAAKLTREYFNVLTAFNGPDALEMVRKESPDIVLLDVMMPGMD
GFEVCEKIRSDPATMHIPVVMVTALSDIADRVRGLEAGADDFLTKPVNDIALFARVRSLV
RLKMMMDEWRLRETTSGQFGVIERSGTMLSESFERASVLVLEDSALDLEKITDTLERDHN
TVTSADTCAKALERALGNPLDLVVVSLTLLNEDGLRLCSQLRSHERTRQVPILLMVDDGD
LGQVAKGLELGANDYVIKPVDRNELLARARTQIRRKRYQERLRSNYEQSLSMALTDSLTG
VFNRRYVNAHLPRLLERAIDSHKPVSVLMFDIDHFKVVNDTYGHAIGDEVLREVSARASR
NLRTFDLVARLGGEEFIVILPDTDGEAALIVAERLRSRIADFPFAVSADRGEINVTVSIG
ISIGGRLGDTAEGLVRRADEALYEAKRSGRNCVIADARADQLEG