Protein Info for MPMX19_01464 in Azospirillum sp. SherDot2

Annotation: Endolytic peptidoglycan transglycosylase RlpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 323 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF03330: DPBB_1" amino acids 62 to 151 (90 residues), 85.4 bits, see alignment E=2.6e-28 TIGR00413: rare lipoprotein A" amino acids 64 to 158 (95 residues), 142.8 bits, see alignment E=6.9e-46 PF05036: SPOR" amino acids 248 to 310 (63 residues), 47.1 bits, see alignment E=2.4e-16

Best Hits

KEGG orthology group: K03642, rare lipoprotein A (inferred from 94% identity to azl:AZL_018140)

Predicted SEED Role

"Rare lipoprotein A precursor" in subsystem Peptidoglycan Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (323 amino acids)

>MPMX19_01464 Endolytic peptidoglycan transglycosylase RlpA (Azospirillum sp. SherDot2)
MRRWRGVSRVVVLVGVAALAACAQKPAGTGPGLPTSGVYKVGKPYQINGVWYYPKEDFSY
DETGIASWYGPGFHEKNTANGEIYDQNELTAAHKTLPMPSLVRVTNLDNGRSIVVRVNDR
GPYANGRIIDMSRRGAQLLGFDGPGTAKVRVQILAEESRAIAAAARQGTPAPLLAEVDGP
PPKAAPRGRIEVSGPSGPATTLAASTGAPRPAVVGAPIPPPATVAGSMAEGRFVPAPVVA
QLPVKAQEAIYVQVGAFGSEENVAKARARLSSIGQRASVSQTRTAGLTLHRVRVGPLDSV
DRADTLLNQIIQAGLTEAKIVVD