Protein Info for MPMX19_01380 in Azospirillum sp. SherDot2

Annotation: K(+)/H(+) antiporter NhaP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 32 to 52 (21 residues), see Phobius details amino acids 58 to 76 (19 residues), see Phobius details amino acids 88 to 111 (24 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 184 to 184 (1 residues), see Phobius details amino acids 186 to 186 (1 residues), see Phobius details amino acids 190 to 212 (23 residues), see Phobius details amino acids 224 to 256 (33 residues), see Phobius details amino acids 270 to 289 (20 residues), see Phobius details amino acids 296 to 321 (26 residues), see Phobius details amino acids 333 to 354 (22 residues), see Phobius details amino acids 361 to 385 (25 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 17 to 385 (369 residues), 155.2 bits, see alignment E=2.4e-49 PF03471: CorC_HlyC" amino acids 491 to 564 (74 residues), 30.7 bits, see alignment E=2.7e-11

Best Hits

KEGG orthology group: K11105, cell volume regulation protein A (inferred from 93% identity to azl:AZL_012490)

Predicted SEED Role

"Na+/H+ antiporter" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (629 amino acids)

>MPMX19_01380 K(+)/H(+) antiporter NhaP (Azospirillum sp. SherDot2)
MEAVSYIILIGSTLLIVSVLTSYLALRVGAPLLLIFLGIGLLAGEDGIGHISFNDAGSAF
LIGSMALAVILFESGFDTKLASYKAAAWPAMTLATVGVAVTTGVVGIAAHYLMGLAWGEA
LLVGAACSSTDAAAVFFLLRVGGITLRDRVRSTLEIESGSNDPVAIMVTILLVETATHGL
ASPIAIVGELVLAFSLGGVMGLAGGWLLVTFINKANFEAGLNPVVTLTFALFIFAVTNVM
GGSGYLAVYAAGLYAGNVKLRGALELRRFHAGLTWLSQIVMFVMLGLLATPREFAGMILP
ALGVAFVLIVVARPAAVWMCLLPFRFSVRETSFIAWVGLRGAVSLLLALVPVLGGLENGQ
LIFNTAFIVVVVSLLVQGSTIGTMARALELIVPPRRGPVERVELELPGNADQELVAYTVH
AKSPAARGQRMPRWAKPSLVIRSGAVVPLHKAKPLQPGDHVYLFTPQHRLTLIDRLYGGS
RALDQNDREFYGDLVLSPDATVEQIAEMYGLPLSMSNARLTLSDLLRNEFGGSCELGDRV
RMGGVELIVRDMEDSIITSVGLALEPARVTSRRRPLYQRLIDIGGRLGGWWNEQSFRRWK
EREKQRACRAGMPAAEPRHDERVESRTEV