Protein Info for MPMX19_01309 in Azospirillum sp. SherDot2

Annotation: Outer membrane efflux protein BepC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 34 to 442 (409 residues), 329.8 bits, see alignment E=1.3e-102 PF02321: OEP" amino acids 38 to 226 (189 residues), 99.2 bits, see alignment E=1.3e-32 amino acids 245 to 429 (185 residues), 109.8 bits, see alignment E=7.4e-36

Best Hits

KEGG orthology group: K12340, outer membrane channel protein TolC (inferred from 96% identity to azl:AZL_013060)

Predicted SEED Role

"Type I secretion outer membrane protein, TolC precursor" in subsystem Multidrug Resistance Efflux Pumps or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (467 amino acids)

>MPMX19_01309 Outer membrane efflux protein BepC (Azospirillum sp. SherDot2)
MTVRSRFARRWLLATALTLTATMGTAVTGGGTAQAQSLEQALAQAYANNPTIGAQRARLR
AVDEGVPQALSGYRPTARVTAGISRSTSESKFDGGSTGSEANAKSVGVTATQPIYDATVA
PAVRRAERLVEAQRATLIASEQSVLLAAAQAYLDIVQNQAILQLQTNNEQVLRRQLDAAR
DRFRVGEYTRTDVSQSESRLSAAIASKISAEGTLRASRATYERLVGAAPGELKAPKPAFR
LPKNLDELVELARANNPNVLSASYTEAAQREAVDQQYGRLLPSVNLSASGTRTYDPGRSS
GIDLNRSDSAQVTAQVTIPLYQAGQPEALVREAKQTANQARLQIEESRRQVTESAVSAWQ
ALQTARASIESYSAQIKAAQIALEGVRQEAQVGSRTVLDVLNQEQELLNARVFLVRAQHD
EMVAAFNVLASSGQLTADRLNLPVQKYDPTANYDKTRGKWFGTSVTE