Protein Info for MPMX19_01232 in Azospirillum sp. SherDot2

Annotation: Macrolide export ATP-binding/permease protein MacB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 284 to 311 (28 residues), see Phobius details amino acids 332 to 364 (33 residues), see Phobius details amino acids 371 to 393 (23 residues), see Phobius details PF12704: MacB_PCD" amino acids 21 to 249 (229 residues), 178.7 bits, see alignment E=1.9e-56 PF02687: FtsX" amino acids 290 to 403 (114 residues), 69.4 bits, see alignment E=2.9e-23

Best Hits

KEGG orthology group: K02004, (no description) (inferred from 94% identity to azl:AZL_013780)

Predicted SEED Role

"Macrolide export ATP-binding/permease protein MacB (EC 3.6.3.-)" in subsystem Multidrug Resistance Efflux Pumps (EC 3.6.3.-)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (410 amino acids)

>MPMX19_01232 Macrolide export ATP-binding/permease protein MacB (Azospirillum sp. SherDot2)
MTAWDALRAALDSLRANPLRSALTMLGIVIGVAAVIAMVAVGAGARDQVLRQIASLGTNL
IMVGQGSIARGGVKLGAGTASSLTEDDALAVLSEIPGVVVTAPSVRWGLQIVAGNQNWGT
VLFGITPDYMDARDWNVATGRGLSDEDVAQANKVVVLGQTVVRNLFGGGDPIGEPVRVFS
TPLTVVGVLAEKGQNTQGQDQDDVIFVPLSTAKRNIPGMAKSNPRFIHTMVVKMRDGTDM
AEAQAQIRDLLRQRHRLVAGQDDDFWMRDLSEVSATRDASSRALSFLLAAVAAVSLLVGG
IGIMNIMLVSVTERTREIGLRLAIGARRRDILVQFLIESTTLSLIGAAVGVALGIGTAMG
VAALAGWPTLIQIDSVVLAVVVSGIVGVFFGLYPARRAARLNPIEALRHE