Protein Info for MPMX19_01078 in Azospirillum sp. SherDot2

Annotation: Thiol:disulfide interchange protein DsbD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 695 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 289 to 313 (25 residues), see Phobius details amino acids 333 to 354 (22 residues), see Phobius details amino acids 373 to 393 (21 residues), see Phobius details amino acids 414 to 440 (27 residues), see Phobius details amino acids 447 to 468 (22 residues), see Phobius details amino acids 483 to 505 (23 residues), see Phobius details amino acids 511 to 530 (20 residues), see Phobius details amino acids 541 to 560 (20 residues), see Phobius details PF11412: DsbD_N" amino acids 55 to 156 (102 residues), 63.8 bits, see alignment E=2.3e-21 PF02683: DsbD_TM" amino acids 290 to 502 (213 residues), 63.6 bits, see alignment E=2.5e-21 PF13899: Thioredoxin_7" amino acids 576 to 662 (87 residues), 53.8 bits, see alignment E=2.6e-18

Best Hits

KEGG orthology group: None (inferred from 87% identity to azl:AZL_015410)

Predicted SEED Role

"Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8)" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange (EC 1.8.1.8)

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.8

Use Curated BLAST to search for 1.8.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (695 amino acids)

>MPMX19_01078 Thiol:disulfide interchange protein DsbD (Azospirillum sp. SherDot2)
MKRHALALLLCLAALAGGGAPVFAQDAVGAWTKAGPLEARLVSAVRGTGDLAALPLGLEL
RLESGWKTYWRSPGDAGFAPRLDWSRSANLGEATLSYPAPHRFSVLGFETAGYDTAVLFP
IQGKPATPGKPVDLALTAELLVCSEICVPQTLELALALPAGPAEPSDVANDVARAQALVP
KGPNGLLRVDSVQGKGSALEVEATAADGFVSPDLFVETDPPLTFSAPKTVFSDNDRHVRL
TLTVTDPQQGLDLAGRAMTLTLVDGDKAVEAPVTASAGAAAPAPGGVGLLAMLGVALLGG
LILNLMPCVLPVLSLKLMSVVKHGGQAPAAVRAGFLASAAGILTSFLLMASVLVGVKAAG
GAVGWGIQFQQPLFLVFMVVLVTLFSANLWGLFEVPLPRALADRLGGDGLAGPFATGMFA
TLLATPCSAPFLGTAVGFALSKGPVEIYAIFATLGVGLALPYLAVAAWPRVAGWLPRPGR
WMATLKTVLGFAMMLTALWLLSVLTAQIGEVAAATVGLMMAGLVLALWVGRSARGTARTA
GPALAGVLAVAAFAMPAAVGPSAGAAPVLAESKARWVPFAEATIREHVAAGRTVFVDVTA
DWCITCQANKKLVLNRGEVAQRMDDPTVVAMRADWTRPDAAIAKFLSDHGRYGIPFNIVY
GPGAPDGLALPELLSEGAVLEALSKAAGKPAGKGV