Protein Info for MPMX19_01046 in Azospirillum sp. SherDot2

Annotation: RNA polymerase sigma factor RpoH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 TIGR02392: alternative sigma factor RpoH" amino acids 12 to 281 (270 residues), 333.4 bits, see alignment E=1.2e-103 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 46 to 279 (234 residues), 97.3 bits, see alignment E=7.4e-32 PF04542: Sigma70_r2" amino acids 50 to 115 (66 residues), 66.8 bits, see alignment E=1.2e-22 PF04545: Sigma70_r4" amino acids 227 to 278 (52 residues), 48.9 bits, see alignment 3.8e-17

Best Hits

Swiss-Prot: 58% identical to RPOH_CAUVN: RNA polymerase sigma factor RpoH (rpoH) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: None (inferred from 97% identity to azl:AZL_015730)

Predicted SEED Role

"RNA polymerase sigma factor RpoH" in subsystem Heat shock dnaK gene cluster extended or Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (296 amino acids)

>MPMX19_01046 RNA polymerase sigma factor RpoH (Azospirillum sp. SherDot2)
MLKKLLTGENASLTRYIEESKRFPILAPDVERDLAIAWRERGNPQALEQLVGSHLRLVIK
IARGFGGYGLPLVDLVAEGNVGLMQAAQKFDPQRGFRFATYATWWIRAAIQEYILHSWSL
VKMGTTAAQKKLFFNLRRLKSQMAELEQGDLSPETVATIAAELDVPETEVVEMNRRLAAN
DSSLDATLSSDGETNWLELLADDRPTQDAMLAEADELALRRRLVGQALDRLDARERRILF
ERRLKDDPSTLEALSQQFSVSRERVRQIEVRAFEKLQKAVLSAAQALRRPVTPMVA