Protein Info for MPMX19_00795 in Azospirillum sp. SherDot2

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 98 to 119 (22 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details PF00672: HAMP" amino acids 195 to 247 (53 residues), 43.3 bits, see alignment 5.7e-15 PF00512: HisKA" amino acids 254 to 319 (66 residues), 33.8 bits, see alignment E=4.2e-12 PF02518: HATPase_c" amino acids 366 to 473 (108 residues), 81 bits, see alignment E=1.3e-26

Best Hits

KEGG orthology group: None (inferred from 93% identity to azl:AZL_010830)

Predicted SEED Role

"Sensor protein basS/pmrB (EC 2.7.3.-)" in subsystem Lipid A modifications or Orphan regulatory proteins (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>MPMX19_00795 Adaptive-response sensory-kinase SasA (Azospirillum sp. SherDot2)
MKHEGAAAAGLHGFVAAGLRLVRTTAFRLALLYLAMFVLSVGLILGVVYRTTAGFLEQEI
GETIALEVAGLQDHYRNYGLPGLVDVVRTRSAVANNNSIYLLTTAAGVILAGNLSGWPAA
VPNASGWTHFKVADYGGVTDRPSTAQAVTFTLPGQFRLLVGRDMSEIDQLRTRMFRSLGW
ILGATALLGLGGGLLMSRGAMRRIEAINRTTRQIMSGDLSDRVPRFGGGDEMDRLAGNLN
AMLDRIERLMTGMKQVTDSVAHDLRTPLTRLRSRIELALLHETEDPEVYRSVLQDTIVEA
DRLLATFTALLSIAEAESGAKRQDFVPVDLAEVVELAADLYEPVADERGQRLSVDIRGKP
VVHGNGQLLAQAVSNLLDNAIKYTPDGGSIALVLDGQAPGRAACIEVADSGPGIPPDMRD
KVLQRFVRLDTARASPGNGLGLSLVDAVATLHGAKLELSDNQPGLKVSLLFPPEARR