Protein Info for MPMX19_00696 in Azospirillum sp. SherDot2

Annotation: Crossover junction endodeoxyribonuclease RuvC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 362 TIGR00228: crossover junction endodeoxyribonuclease RuvC" amino acids 18 to 168 (151 residues), 143.4 bits, see alignment E=2.8e-46 PF02075: RuvC" amino acids 19 to 165 (147 residues), 149.2 bits, see alignment E=8.3e-48 PF04480: DUF559" amino acids 224 to 329 (106 residues), 121.9 bits, see alignment E=1.1e-39

Best Hits

Predicted SEED Role

"Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)" in subsystem DNA-replication or RuvABC plus a hypothetical (EC 3.1.22.4)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.22.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (362 amino acids)

>MPMX19_00696 Crossover junction endodeoxyribonuclease RuvC (Azospirillum sp. SherDot2)
MFARAGRSEATVPSPVRLLGIDPGLRHTGWGIIDVAGNRLSHVADGAVHSDDRCPLAERL
VQLHDALSAVVERYCPDEAAVEETFVNNNAVSTLKLGQARAVALLVPAQAGLAVAEYANN
MVKKAVVGQGRAEKAQVQTMVRLLLPGCEIASPDAADALAIAICHAHHRASWTMWRRGDI
SSQRAQSALSRPGRGRGPAAGGEGEGLSVTDVSIQAKRLPTPQETERARVLRRDSTEVEK
MLWQKLRNGQLGAKFRRQEPIFGFTVDFVSHDHRLIIELDGGQHAEQRASHDERRTRMLE
QAGFRIMRFWNNDVGDNLDGVLTTIKARLDETSVLRRPVAVANPSPGPAGHPLPGRERDS
ES