Protein Info for MPMX19_00658 in Azospirillum sp. SherDot2

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 699 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 248 to 267 (20 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 282 to 407 (126 residues), 90.9 bits, see alignment E=3.5e-30 PF00989: PAS" amino acids 287 to 399 (113 residues), 56.3 bits, see alignment E=1.1e-18 PF08448: PAS_4" amino acids 295 to 404 (110 residues), 51.7 bits, see alignment E=3.2e-17 PF13426: PAS_9" amino acids 303 to 401 (99 residues), 47.8 bits, see alignment E=5.3e-16 PF08447: PAS_3" amino acids 309 to 394 (86 residues), 31.4 bits, see alignment E=6.8e-11 PF00512: HisKA" amino acids 425 to 492 (68 residues), 35.3 bits, see alignment E=3.3e-12 PF02518: HATPase_c" amino acids 536 to 673 (138 residues), 71 bits, see alignment E=3.9e-23

Best Hits

KEGG orthology group: K11711, two-component system, LuxR family, sensor histidine kinase DctS [EC: 2.7.13.3] (inferred from 84% identity to azl:AZL_009440)

Predicted SEED Role

"two-component hybrid sensor and regulator"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (699 amino acids)

>MPMX19_00658 Adaptive-response sensory-kinase SasA (Azospirillum sp. SherDot2)
MALVVVLLGAFLWLLQRNEREEEALALIKDALWVEQNLHFQLASDEDKLERLAETLGRVE
VDLRQFAAMARLVVNTNPAIERVLWLDAQGRTLLAEPPLPGNGGTDAPSEPAGAEGMARD
DAVRIARSSGLRAYGAPYRIDATDRGFDAAFPLFRDGAFAGTLVGVFSFEAMLTHHVPWW
FAQRYQLEVVDATGTVLGSKSRMSVPGSMAGPAPDPARSHLIPFDPPGHGMALVATAYPS
DSNVTRTVLVAAIFALTGSALWSLWSLRRHIAGRLRAEEALREEHAFRKAMEDSLTVGMR
ARDLEGRITYVNPAFCRMVGLDADDLIGRGPPAPYWLPEEIDRAEAAFQDVLAGRAPESG
LEMRFQRPDGERFEALIYEAPLIDANGRQTGWMGSVLDITERKRAEELARQQQERLQQTS
RLITMGEMASTLAHELNQPLSAIASYCTGCLNRLRSDRCDTQEVAAALEKLAAQAKRAGL
VVRRIHDFVRKRDPRVAPCSLAEVLEDCVGLAGSDAARLGVRVELDAPADLPPVTGDRIL
LQQVVLNLMRNGIEAMARTPRADRRLTVTVRQTDCDGGEEAGKDGGKDGARLLLTEIRDH
GCGVAPDVADRLFSPFFTTKREGMGMGLNICRSIVEHHRGRLWFETVTPEGDGNGDATGA
DAAGTRFLFTLPVHARTPDRTTGPYPAGPFPDHTAEAAE