Protein Info for MPMX19_00528 in Azospirillum sp. SherDot2

Annotation: Beta-barrel assembly-enhancing protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 881 PF13432: TPR_16" amino acids 5 to 63 (59 residues), 26.7 bits, see alignment 5.4e-09 amino acids 81 to 131 (51 residues), 36.7 bits, see alignment 4.1e-12 amino acids 141 to 203 (63 residues), 28.1 bits, see alignment 2e-09 amino acids 183 to 237 (55 residues), 19.3 bits, see alignment 1.2e-06 amino acids 241 to 303 (63 residues), 19.6 bits, see alignment 9.5e-07 amino acids 310 to 373 (64 residues), 34.9 bits, see alignment 1.6e-11 amino acids 354 to 406 (53 residues), 16.9 bits, see alignment 6.6e-06 PF13374: TPR_10" amino acids 35 to 66 (32 residues), 16.2 bits, see alignment (E = 8e-06) amino acids 107 to 129 (23 residues), 15.8 bits, see alignment (E = 1e-05) amino acids 139 to 164 (26 residues), 18.8 bits, see alignment (E = 1.2e-06) amino acids 272 to 300 (29 residues), 17.8 bits, see alignment (E = 2.5e-06) PF13424: TPR_12" amino acids 101 to 165 (65 residues), 37 bits, see alignment 3e-12 PF14559: TPR_19" amino acids 112 to 173 (62 residues), 26.9 bits, see alignment 4.5e-09 amino acids 147 to 206 (60 residues), 25.7 bits, see alignment 1e-08 amino acids 283 to 345 (63 residues), 29.5 bits, see alignment 7.1e-10 PF13181: TPR_8" amino acids 136 to 167 (32 residues), 15.7 bits, see alignment (E = 1.3e-05) amino acids 170 to 202 (33 residues), 16.3 bits, see alignment (E = 8e-06) amino acids 273 to 303 (31 residues), 17.8 bits, see alignment (E = 2.5e-06) PF07719: TPR_2" amino acids 272 to 303 (32 residues), 24 bits, see alignment (E = 2.5e-08) PF13176: TPR_7" amino acids 275 to 302 (28 residues), 14.1 bits, see alignment (E = 3.8e-05) PF13844: Glyco_transf_41" amino acids 489 to 646 (158 residues), 139.3 bits, see alignment E=1.2e-43 amino acids 655 to 839 (185 residues), 143 bits, see alignment E=9.2e-45

Best Hits

KEGG orthology group: None (inferred from 78% identity to azl:AZL_007110)

Predicted SEED Role

"TPR domain protein, putative component of TonB system" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (881 amino acids)

>MPMX19_00528 Beta-barrel assembly-enhancing protease (Azospirillum sp. SherDot2)
MTSFARGVAAENAGRLEEARARYLDVLRAEPRNPAALHRLGVVELRLGNPRDAVVLFQKS
LAIAKDLEVYLDFGAAMAGMARWDAAATVYAAALRVAPASADAHYGLAMALHRQGRPQDA
EPHYRKVLAAFSHLGEVHNNLGVALQDLGRFAEAAAAHREAARIDPTDAASWSKLGVALH
AIGQGAEAEAAFRKALGLAPQDADCWHNLSGLLDADGRPAEALAAGRLAVALDPGSARNW
LALGNAAGAARSLEEAWRATSAAARLEPSSPAARNNLASALQELGRWREAVAEYRAALEL
QPDFPVAEINLAQALSGLREADGALAVLRALLARQPANGEAWRRLGSVLAEAVRPDAAVA
VLRKAVALAPGEPDAQADLAMAAAMAGWSTQSADACRRVLRLVPGHAAALGQLVHQQRLL
CDWRDLDGLEVELLRQVRAGAEGVSPFDVLSCASTLADQQSAAARWAVAKARGTGTVTRP
AATAVIAAAGDGRLRIGYLSSDFREHAMGHLMVDALETHDRSRFAVTAYSTGLDDGSALR
QRFQRGIERFVDLRRHTDADAARTIAADGIDILVDLTGFTSFSRTSILAARPAPVQVNWL
GYPGTLGAGYVDYIVADPTVIAPGEDGFFSERVVRLPDCYQPNDRRRAIAEATPTRRDCG
LPEDGFVFCCFNSAYKLTPALFDGWARILAAVPGSVLWLYAGNPQVAVNLRREGEARGLA
PHRLVFAQPLPHAGHLARHRLADLFLDTLPYNAHTTASDALWAGLPVLTRRGTTFAGRVA
ASLLRAAGLPELIVDGQEAYEAEAVALARSPGRLRDLRQRLALNRPVCPLFDTPRFTRHL
EAAYRAMWDIHRAGGAPRPITVTAEDAGGPASAMQGEGENA