Protein Info for MPMX19_00515 in Azospirillum sp. SherDot2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01575: MaoC_dehydratas
  • amino acids 43 to 138 (96 residues), 52.7 bits, E=3.3e-18
• PF01515: PTA_PTB
  • amino acids 261 to 473 (213 residues), 143.1 bits, E=1.4e-45

Best Hits

KEGG orthology group: K00625, phosphate acetyltransferase [EC: 2.3.1.8] (inferred from 96% identity to azl:AZL_006980)

Predicted SEED Role

"Phosphate acetyltransferase (EC 2.3.1.8)" in subsystem Ethanolamine utilization or Fermentations: Lactate or Fermentations: Mixed acid or MLST or Propanediol utilization or Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate or Threonine anaerobic catabolism gene cluster (EC 2.3.1.8)

MetaCyc Pathways

• mixed acid fermentation (14/16 steps found)
• hexitol fermentation to lactate, formate, ethanol and acetate (16/19 steps found)
• heterolactic fermentation (15/18 steps found)
• superpathway of L-threonine metabolism (15/18 steps found)
• L-threonine degradation I (6/6 steps found)
• ethanolamine utilization (5/5 steps found)
• superpathway of N-acetylneuraminate degradation (17/22 steps found)
• pyruvate fermentation to acetate and (S)-lactate I (4/4 steps found)
• pyruvate fermentation to acetate and lactate II (4/4 steps found)
• pyruvate fermentation to acetate I (3/3 steps found)
• pyruvate fermentation to acetate II (3/3 steps found)
• pyruvate fermentation to acetate IV (3/3 steps found)
• pyruvate fermentation to acetate VII (3/3 steps found)
• superpathway of acetate utilization and formation (3/3 steps found)
• acetate and ATP formation from acetyl-CoA I (2/2 steps found)
• superpathway of fermentation (Chlamydomonas reinhardtii) (7/9 steps found)
• acetylene degradation (anaerobic) (4/5 steps found)
• acetyl-CoA fermentation to butanoate (5/7 steps found)
• purine nucleobases degradation II (anaerobic) (17/24 steps found)
• (S)-lactate fermentation to propanoate, acetate and hydrogen (9/13 steps found)
• sulfoacetaldehyde degradation I (1/2 steps found)
• superpathway of Clostridium acetobutylicum acidogenic fermentation (6/9 steps found)
• (S)-propane-1,2-diol degradation (3/5 steps found)
• superpathway of taurine degradation (3/6 steps found)
• lactate fermentation to acetate, CO₂ and hydrogen (Desulfovibrionales) (4/8 steps found)
• sulfolactate degradation II (1/4 steps found)
• L-lysine fermentation to acetate and butanoate (5/10 steps found)
• superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (10/17 steps found)
• methanogenesis from acetate (2/6 steps found)
• superpathway of sulfolactate degradation (2/6 steps found)
• gallate degradation III (anaerobic) (5/11 steps found)
• superpathway of L-alanine fermentation (Stickland reaction) (3/9 steps found)
• superpathway of methanogenesis (5/21 steps found)
• superpathway of L-lysine degradation (13/43 steps found)

KEGG Metabolic Maps

• Propanoate metabolism
• Pyruvate metabolism
• Taurine and hypotaurine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.8

Use Curated BLAST to search for 2.3.1.8

Protein Sequence (489 amino acids)

>MPMX19_00515 hypothetical protein (Azospirillum sp. SherDot2)
MDTAIAAPSAAPAGRSGIVPTGKNGSPMIENVTFEEIRIGQQASLSRRLTMSDIELFATV
SGDLNPSHVDEDYAVDHKVVGHGMWSGSLISAVLGTLLPGPGTVYVGQDLRFERPVLLGD
IVTVTVTARSKDAARKTVVFDCLCLNQDGRTVATGVAEVIAPTEKVCRAAAELPQVQVIR
HDGHELMLKKCESLPPVPTAVVHPCDESSLRGAVEAAEANLIDPVLVGPESKIRSVADAC
GLDISRYRIVDVAHSHASAETGVRLARTGECEAVMKGSLHTDELMGEVVRKETGLRTGRR
LSHVFVMNVPTYPRPLLITDAAINIYPTLEDKVSIVQNAIDLAKVLGTEVPRVAILSAVE
TINTKIASTLEAAALCKMADRGQITGGILDGPLAFDNAISREAAITKGIKSEVAGQADIL
LVPDLEAGNMLAKQLSFLAHADAAGIVLGARVPIILTSRADNVRTRLASCAVAVLSAAAR
RRGAAPAAE