Protein Info for MPMX19_00435 in Azospirillum sp. SherDot2

Annotation: Bicyclomycin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 75 to 94 (20 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 162 to 183 (22 residues), see Phobius details amino acids 213 to 237 (25 residues), see Phobius details amino acids 250 to 269 (20 residues), see Phobius details amino acids 282 to 323 (42 residues), see Phobius details amino acids 336 to 361 (26 residues), see Phobius details amino acids 368 to 391 (24 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 9 to 383 (375 residues), 320.9 bits, see alignment E=7.7e-100 PF07690: MFS_1" amino acids 18 to 357 (340 residues), 154.1 bits, see alignment E=9.8e-49 PF05977: MFS_3" amino acids 41 to 386 (346 residues), 30 bits, see alignment E=3.8e-11 PF00083: Sugar_tr" amino acids 44 to 113 (70 residues), 38.1 bits, see alignment E=1.9e-13 PF06609: TRI12" amino acids 46 to 171 (126 residues), 27.1 bits, see alignment E=3e-10

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 90% identity to azl:AZL_006220)

Predicted SEED Role

"Multidrug resistance transporter, Bcr/CflA family" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (400 amino acids)

>MPMX19_00435 Bicyclomycin resistance protein (Azospirillum sp. SherDot2)
MPRPDSLTIRILLTALVAFGPLSTDLYLPSLPTLVRVFGTDVATVQLTLSIFLVGFAVSQ
LVYGPMSDRFGRRPTLLVGVTIYLAASAVCAMTSSIDALIAARFFQALGACCGPVVARAV
VRDVFGRDRAATVLAYMSMAMALAPAVGPMLGGVLTEWFGWRANFVLLTVFACGILAAVW
SLLGETNAHRDEDALRPSRLAANYLLLLRNRGFLGYVLVVAFSYSGIFSFISGSSFVLIE
QMHLTPAQYGASFGAVVLGYMLGTFLAGRLTPRLGGARMIRIGTLLSMGGGLVGGALALA
GVLHLLAIVVPVFLFILGTGLTLPNASANAVGPYATMAGLASSLLGFAQMAIAAIIGIVV
GHMNDGTALPMMGAIGLVALGALLAHRLLVIPAATSGRSA