Protein Info for MPMX19_00304 in Azospirillum sp. SherDot2

Annotation: Phosphatidylcholine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 transmembrane" amino acids 12 to 37 (26 residues), see Phobius details amino acids 43 to 60 (18 residues), see Phobius details amino acids 76 to 97 (22 residues), see Phobius details amino acids 104 to 124 (21 residues), see Phobius details amino acids 131 to 149 (19 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 183 to 204 (22 residues), see Phobius details amino acids 210 to 230 (21 residues), see Phobius details

Best Hits

Swiss-Prot: 56% identical to PCS_PSEAE: Phosphatidylcholine synthase (pcs) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K01004, phosphatidylcholine synthase [EC: 2.7.8.24] (inferred from 95% identity to azl:AZL_005000)

Predicted SEED Role

"Phosphatidylcholine synthase (EC 2.7.8.24)" in subsystem ZZ gjo need homes (EC 2.7.8.24)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.24

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (235 amino acids)

>MPMX19_00304 Phosphatidylcholine synthase (Azospirillum sp. SherDot2)
MSAAYGITHRLSAWGVHIFTASGAVLGLLGLLAAAAGDAKLCLMWLGIALVVDGVDGTLA
RRVSVKQVLPGIDGSALDLVIDYLTYVVVPAVFMHRFGLLPEGLVSIALAAWVLLTALYC
FANVGMKSGDNYFVGFPAIWNVVALYLWLLDLNPWFNAAVVVALGLLTFTTVKFLHPFRV
KALMALNIAVTTVWLLCCIALVVLEPARPGWLFGLWLATSVYYAAVCAWRTLRGP