Protein Info for MPMX19_00213 in Azospirillum sp. SherDot2

Annotation: Heme A synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 transmembrane" amino acids 21 to 42 (22 residues), see Phobius details amino acids 106 to 124 (19 residues), see Phobius details amino acids 136 to 154 (19 residues), see Phobius details amino acids 169 to 191 (23 residues), see Phobius details amino acids 212 to 235 (24 residues), see Phobius details amino acids 270 to 291 (22 residues), see Phobius details amino acids 303 to 325 (23 residues), see Phobius details amino acids 331 to 349 (19 residues), see Phobius details PF02628: COX15-CtaA" amino acids 22 to 344 (323 residues), 352.4 bits, see alignment E=1.1e-109

Best Hits

Swiss-Prot: 46% identical to CTAA_XANP2: Heme A synthase (ctaA) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)

KEGG orthology group: K02259, cytochrome c oxidase subunit XV assembly protein (inferred from 92% identity to azl:AZL_003430)

Predicted SEED Role

"Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (357 amino acids)

>MPMX19_00213 Heme A synthase (Azospirillum sp. SherDot2)
MTAFASDSLAAAARPNPNRPIAVWLLVCAAMVLAMAVIGAITRLTESGLSMVEWKPLIGI
LPPLSSAEWNRVFDLYKATPEFRIYNSHMDLAGFQSIFWWEWFHRLWGQLIGFVFLIPFL
RFWMQGRISSELWPKLAGLFLLGGLQGGIGWFMVKSGLVDSPNVSHYRLALHLSTAILIY
ALLLRTALGLLDPLPMAGWRPESASLRRHTRWALGLVAVTIVWGAFVAGSDAGFAYNTFP
LMNGHWIPPEVDTLTPWWLNPVENTAAIQLIHRALAILTGVVVLVLAARVLNARLPGRAG
RAALASGAMVLLQIAMGVATLLTVVWTPIAAAHQAGAILMVSMLVWLLFELRPIGRE