Protein Info for MPMX19_00061 in Azospirillum sp. SherDot2

Annotation: L-lysine 2,3-aminomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 345 TIGR03822: lysine-2,3-aminomutase-related protein" amino acids 5 to 321 (317 residues), 485.3 bits, see alignment E=7.4e-150 TIGR00238: KamA family protein" amino acids 23 to 311 (289 residues), 241.9 bits, see alignment E=8.7e-76 PF04055: Radical_SAM" amino acids 99 to 247 (149 residues), 47.9 bits, see alignment E=1.8e-16 PF12544: LAM_C" amino acids 291 to 343 (53 residues), 27.1 bits, see alignment 4.1e-10

Best Hits

Swiss-Prot: 39% identical to KAMA_ACESD: L-lysine 2,3-aminomutase (kamA) from Acetoanaerobium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIMB 10654)

KEGG orthology group: K01843, lysine 2,3-aminomutase [EC: 5.4.3.2] (inferred from 94% identity to azl:AZL_026200)

MetaCyc: 38% identical to lysine 2,3-aminomutase (Clostridium subterminale)
Lysine 2,3-aminomutase. [EC: 5.4.3.2]

Predicted SEED Role

"Lysyl-lysine 2,3-aminomutase"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (345 amino acids)

>MPMX19_00061 L-lysine 2,3-aminomutase (Azospirillum sp. SherDot2)
MKALHSVSDLVAAGLMTPEAGDAVRTVADRYAVALTPYLRETLAGRMDPQDPLYAQYVPS
PAEAYSTPEELEDPIGDVARSPVKGIVHRYPDRVLLKPLHACAVYCRFCFRREMVGPGGE
ALTPDELDAALAYIRDHEEVWEVVVTGGDPLLLSPRRLRGIVQALSAMPHVGVVRLHSRI
PAADPDRVTPELVEALTAPDLATWVAVHINHADELTPPVRAALARLVEAGIPLVGQTVLL
KGINDSHAALEALFRGMVRNRVKPYYLHHPDLAAGTSHFRPTLAEGQALVNGLRGKLSGL
CQPTYVLDIPGGHGKAPAAPAWIEKQGEGGYRVTDFTGRVHDYRG