Protein Info for MPMX19_00050 in Azospirillum sp. SherDot2

Annotation: Pyridoxal phosphate homeostasis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 TIGR00044: pyridoxal phosphate enzyme, YggS family" amino acids 6 to 221 (216 residues), 174.5 bits, see alignment E=1.3e-55 PF01168: Ala_racemase_N" amino acids 10 to 222 (213 residues), 85.3 bits, see alignment E=2.7e-28

Best Hits

Swiss-Prot: 42% identical to PLPHP_DEIRA: Pyridoxal phosphate homeostasis protein (DR_1368) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

KEGG orthology group: K06997, (no description) (inferred from 91% identity to azl:AZL_026290)

Predicted SEED Role

"Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (226 amino acids)

>MPMX19_00050 Pyridoxal phosphate homeostasis protein (Azospirillum sp. SherDot2)
MADSVTARLDSVRRAIAETESACGRDKNTVTLVAVSKTHPAEAVEEALAAGQRVFGENRV
QEAKGKFPALKERFPDLELHLIGPLQTNKVKDAVALFDVIQTLDRPKLAEALAEEMAKSG
RRPRCLIEVNTGEEPQKAGIAPAEVEAFLADCRDRLGLPVAGLMCIPPVDEEPAMHFALL
AGMARRLGLPEISMGMSGDYETAVRFGATHVRVGTAIFGARPYPAQ