Protein Info for MIT1002_04022 in Alteromonas macleodii MIT1002

Annotation: trans-aconitate 2-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 PF13489: Methyltransf_23" amino acids 76 to 178 (103 residues), 35.1 bits, see alignment E=2.3e-12 PF13649: Methyltransf_25" amino acids 84 to 173 (90 residues), 37 bits, see alignment E=9.2e-13 PF08242: Methyltransf_12" amino acids 84 to 175 (92 residues), 33.8 bits, see alignment E=9.4e-12 PF08241: Methyltransf_11" amino acids 84 to 177 (94 residues), 30.7 bits, see alignment E=7.9e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (244 amino acids)

>MIT1002_04022 trans-aconitate 2-methyltransferase (Alteromonas macleodii MIT1002)
MTPEETGKAYDTITHLWTRPEFNQKNGLTAYQKALSFLAGTPSQEPDTVPSEALDKGEAH
DKSEAPNKGEASNNDKPKKRGYALDIGCGCTNRFVPIIESAGLTYEGIDVSKDMLAIATS
QLPAHTFYCADVCTFTIPKHYSFISAWDSFWHIPLTQQEPLLKKLVDHLDDDGVLLFSCG
GTDESGQHTNEVMGPEVYYASLGLHRYIEILIEAGGFVRHVEFDQHPELHTIIIVQKRTA
QKTQ