Protein Info for MIT1002_03837 in Alteromonas macleodii MIT1002

Annotation: catecholate siderophore receptor CirA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 981 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details TIGR01782: TonB-dependent receptor" amino acids 43 to 981 (939 residues), 604.5 bits, see alignment E=2e-185 PF07715: Plug" amino acids 61 to 164 (104 residues), 63.6 bits, see alignment E=2.3e-21 PF00593: TonB_dep_Rec_b-barrel" amino acids 435 to 947 (513 residues), 79.7 bits, see alignment E=4.5e-26

Best Hits

KEGG orthology group: None (inferred from 88% identity to amc:MADE_03792)

Predicted SEED Role

"Predicted b-glucoside-specific TonB-dependent outer membrane receptor" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (981 amino acids)

>MIT1002_03837 catecholate siderophore receptor CirA (Alteromonas macleodii MIT1002)
MKNTPFKKTQLATSMALLMGSTLALPSYAQESEAVTPAEGEVEVIQVSGIRGSMIRSMDL
KRSSSGVVDAISAEELGKFPDTNLAEALQRITGVSISRSNGEGSEITVRGFGPEFNLITL
NGRQMPGTGFTRSFNLANLSSEGVNTLELQKTARAENPSGGLGATVNIITMKPLAQSGQN
ATFSVKGIYDSSNEAGDDVTPEIAGVYSNTFADDMFGFGLSFSHQERDFQQQAANIQGWQ
LQENAALPDLDPENVVDNRTNITDAAFFPKDMNYSITDVQRERSNAQVTFQFRPVDDFTA
TIDYTATRATTGTNTVGWGIWNNFGANINAYELDENGTAVYADISGDDGSFTASRETTRV
DARSIGVNLDWVVSDDWHFRLDYHDSYNEIDNGYDKGLGSSGQIILGSNQLESKVYDYRA
GEIPQVYVNWNNGTNEILPSEIDSNFSQFIYSPGRSDIEQLQLDGTWYNSAFDIPLVKID
FGYARTEQALTGFEAWSGLRGGPGFSPSFTEIFPDSMFIRNDTSGFLDAFDGGGAGMNPG
YYYTYDFDEAIARQLAFITGDVVGESNAYSIDPYFSGAPSVSNVEEITDSIYVQSEWDFE
VGDYYVQINAGVRYEETEVPSSAEVRVPVQVNWVAASEWITQFEDELQVQDFTGEYDILL
PMFDVKVDVTDDIVARFSWGKSITRAPIGLLQGGLAFSGSPKIGARTASAGNTSLLPFES
TNLDLSFEWYYDESSMLAVGLFRKSVENYITTTGQDQQFEGLRDIYQGPRWNEAVTALTA
AGEQATDSAIYNYFIDNGYADENGVVTPNADDPLITWRTTQPGNSSDSKTVEGIELAIQH
TFGDTGFGFGANATLVDGDVEYDPYNLNEQDPLVGISDSANFQVFYEKEGLSVKVTYAWR
SDYVVGIGQAQGSSDNPATQFDTFGQVDASINYDVNEHLTVFLEGVNINDETERGYGRFE
EQFLFARQYGPRYTLGARYTF