Protein Info for MIT1002_03679 in Alteromonas macleodii MIT1002

Annotation: EAL domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 PF00563: EAL" amino acids 68 to 188 (121 residues), 38.3 bits, see alignment E=9.8e-14 PF08668: HDOD" amino acids 197 to 317 (121 residues), 41.3 bits, see alignment E=1.2e-14

Best Hits

KEGG orthology group: K07181, putative signal transduction protein containing EAL and modified HD-GYP domains (inferred from 95% identity to amc:MADE_03534)

Predicted SEED Role

"Predicted signal transduction protein" in subsystem Flagellar motility

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (411 amino acids)

>MIT1002_03679 EAL domain protein (Alteromonas macleodii MIT1002)
MFAFIARQPILDKSKSVFAYELLFRDGKSGAYPEHNEEKAKYISEHFHPLGLDDISGEKT
SFITFSSDTIISRFPTSLNPESVVVELADPTDNTSGLFEACQHIKQLGFKLAIDDPMMVG
SKHDIFPLIDIVKVDVTKTRFETIEKHIPRYHDANVQLVAEQVDTQDNFSTCVDLGFDFF
QGYFFSQPEARILRQLPASKMNIVDLMGESSSSDFDIDRISQIIERDATLSFLLLKFINN
PTINKRYKITSLKHALNYMGEVEIKKFIALLSLTNLGDEKPLEIIHMSLVRAKFFDLLAE
RRGLRNNPPISFLVGLFSLLEGLLDQSMTDIVKQLPLSDEVNDALLGKNLEMNSYMTLVR
AFESALWMNVIKQAKVLNIDQKQLHMLYNQAIIWGNGVRSAISSHYPRAIA