Protein Info for MIT1002_03493 in Alteromonas macleodii MIT1002

Annotation: Arginine repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 154 PF01316: Arg_repressor" amino acids 5 to 72 (68 residues), 72.8 bits, see alignment E=1.6e-24 TIGR01529: arginine repressor" amino acids 11 to 150 (140 residues), 144 bits, see alignment E=1.7e-46 PF02863: Arg_repressor_C" amino acids 81 to 148 (68 residues), 77.8 bits, see alignment E=4.6e-26

Best Hits

Swiss-Prot: 79% identical to ARGR_COLP3: Arginine repressor (argR) from Colwellia psychrerythraea (strain 34H / ATCC BAA-681)

KEGG orthology group: K03402, transcriptional regulator of arginine metabolism (inferred from 98% identity to amc:MADE_00735)

Predicted SEED Role

"Arginine pathway regulatory protein ArgR, repressor of arg regulon" in subsystem Arginine Biosynthesis extended or Arginine Deiminase Pathway or Arginine and Ornithine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (154 amino acids)

>MIT1002_03493 Arginine repressor (Alteromonas macleodii MIT1002)
MANAKQELLIKAFKEILKAESYGSQGEIVDALKAQGFDNISQSKISRMLSKFGAVRTRNA
RGDMVYCLPPELGMPTAKSPLKQLVLDIVHNNVMVIIRTSPGAAQLIARLLDSLSKKDGV
LGTIAGDDTIFIAPADVARIEELRQRVEDLFENV