Protein Info for MIT1002_03460 in Alteromonas macleodii MIT1002

Annotation: Allantoin transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 transmembrane" amino acids 40 to 60 (21 residues), see Phobius details amino acids 66 to 87 (22 residues), see Phobius details amino acids 119 to 141 (23 residues), see Phobius details amino acids 153 to 178 (26 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details amino acids 234 to 255 (22 residues), see Phobius details amino acids 276 to 299 (24 residues), see Phobius details amino acids 316 to 337 (22 residues), see Phobius details amino acids 357 to 375 (19 residues), see Phobius details amino acids 382 to 407 (26 residues), see Phobius details amino acids 428 to 446 (19 residues), see Phobius details amino acids 466 to 485 (20 residues), see Phobius details TIGR00800: NCS1 nucleoside transporter family" amino acids 21 to 452 (432 residues), 390.1 bits, see alignment E=6.3e-121 PF02133: Transp_cyt_pur" amino acids 28 to 474 (447 residues), 398.5 bits, see alignment E=1.9e-123

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 95% identity to amc:MADE_00768)

Predicted SEED Role

"Cytosine/purine/uracil/thiamine/allantoin permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (500 amino acids)

>MIT1002_03460 Allantoin transport protein (Alteromonas macleodii MIT1002)
MDNTNNQTMTKPSHYDGDLWNEDLAPTNAETRTWVWKDYAALWVAMVVCVPTYLLSAGLV
SEGMNWYQAVITVLLGNIIVLVPMMLIGHAGAKYGLPFPVLLRSAFGTKGAKIPALARGL
VACGWFGINTWVGGSAIYVILNSVSGDAFVGQALPFLGIDITQTLCFFAFWAMHLVFIKH
GTESIRWLETFAAPFLILMGLALLGWAYVNAGGFGEMLSTPSQFVEGGAKEGQFWTAFFA
GLTSMVGFWATMALNIPDFTRFAKSQKDQMLGQAIGLPLPMALFAFIGVAVTSATVTIYG
EAIWDPVALAGRMGGMGVVLALAALALATLTTNLAANMVAPAYGFSNMAPSKISFKMGGY
ITAGIGVAIFPWKLLETAGGYLFTWLTGYSALLGPIAGILIADYFILRKSTLNIDALFQH
AGEYGANNGWNMAGVTALVIGILPNIPGFMHAAGFVESVPAVFDTLYAYAWFVGLIIASM
VYLLLSNRAPVTMQAKSASQ