Protein Info for MIT1002_03324 in Alteromonas macleodii MIT1002

Annotation: Chemotaxis regulator BdlA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 PF13426: PAS_9" amino acids 30 to 133 (104 residues), 42.9 bits, see alignment E=1.6e-14 amino acids 154 to 256 (103 residues), 39.2 bits, see alignment E=2.2e-13 TIGR00229: PAS domain S-box protein" amino acids 36 to 134 (99 residues), 40 bits, see alignment E=2e-14 amino acids 143 to 263 (121 residues), 49.2 bits, see alignment E=2.7e-17 PF08448: PAS_4" amino acids 153 to 258 (106 residues), 43.7 bits, see alignment E=8.8e-15 PF00989: PAS" amino acids 153 to 245 (93 residues), 26.1 bits, see alignment E=2.3e-09 PF08447: PAS_3" amino acids 167 to 249 (83 residues), 38.2 bits, see alignment E=4.2e-13 PF00015: MCPsignal" amino acids 275 to 433 (159 residues), 128.9 bits, see alignment E=5.8e-41

Best Hits

Swiss-Prot: 39% identical to BDLA_PSEAE: Biofilm dispersion protein BdlA (bdlA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 55% identity to mpc:Mar181_1035)

Predicted SEED Role

"Methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>MIT1002_03324 Chemotaxis regulator BdlA (Alteromonas macleodii MIT1002)
MFNKHLVKENEALREELHILKQVRDGLREEMIFLNLNERGEIEAVNEVFEKELGYSLSQV
KGHRFFEFVPEIARSTPHFKKLKDSIEQRVHYWGAIEFLRENGEEAWLRGVVEPIFDGKG
NIHKFSVNLNDLTRTIANSKEHEDLVAALHKSNAVIEFDLNGNIQDANEAFLKAVKYRLN
DIKGQHHRIFCDTEYANSREYKTFWERLTQGEFVAGRFERFDAHGNTIWLEATYNPICDS
HGRMYKVVKLATDITEQVARENAVSSAADIAYRSSNTTDQIATRGKEVISELLSEMSSLS
QQMDRAKEGINALDAQSQQIATIIGSISAIAEQTNLLALNAAIEAARAGDQGRGFAVVAD
EVRQLASRTTEATEEIINVVKHNQTLATDAVNLVNEGDEKAQSGLNYAREAGEVIEQIQD
GAKEVVDAVGQFSSRLGS