Protein Info for MIT1002_03215 in Alteromonas macleodii MIT1002

Annotation: putative ATP-binding protein involved in virulence

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 transmembrane" amino acids 257 to 276 (20 residues), see Phobius details PF13304: AAA_21" amino acids 43 to 325 (283 residues), 70.8 bits, see alignment E=1.1e-23

Best Hits

Predicted SEED Role

"SMC domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (369 amino acids)

>MIT1002_03215 putative ATP-binding protein involved in virulence (Alteromonas macleodii MIT1002)
MLTYFSVQGFRNFKDKLEFDLRSTNKYEFNTHALKNGTVNHSVIYGENGSGKSNVGLAIL
DIVSHVIPDSTVQINTLKDNFLNADTDEQHANFEYEFEIEGHEVVYRYGKTDDLSLVYES
LHIDKQLVAEINRDEGHKAFFDLDGSENLKTDISRADISIIRYLSMSVLDETRLNYIFDK
FIEFVGGMVFFRSLNRTEYQGQRISSSKLSDEIIGKGKVQEFEKFLNEVGVNCNLDVQGA
SDDQYIVFKYRNKTIEFSRIASTGTLSLGIFYYWYLQLCDKKIKFAFIDEFDAFYHFELS
RKIVNKLSELECQTVLTTHNLSLLDNDLLRPDCYFEVSDNKIAPFSSLVHKELRKAHNIE
KIYRGMRIE