Protein Info for MIT1002_03181 in Alteromonas macleodii MIT1002

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 PF00009: GTP_EFTU" amino acids 8 to 198 (191 residues), 196.6 bits, see alignment E=9.1e-62 TIGR00231: small GTP-binding protein domain" amino acids 8 to 154 (147 residues), 89.5 bits, see alignment E=2.1e-29 TIGR01394: GTP-binding protein TypA/BipA" amino acids 9 to 603 (595 residues), 967 bits, see alignment E=3e-295 PF01926: MMR_HSR1" amino acids 12 to 133 (122 residues), 28.9 bits, see alignment E=3.2e-10 PF22042: EF-G_D2" amino acids 210 to 294 (85 residues), 34.7 bits, see alignment E=4.8e-12 PF03144: GTP_EFTU_D2" amino acids 223 to 293 (71 residues), 40.4 bits, see alignment E=9.6e-14 PF00679: EFG_C" amino acids 401 to 482 (82 residues), 80.8 bits, see alignment E=1.9e-26 PF21018: BipA_C" amino acids 489 to 597 (109 residues), 156.1 bits, see alignment E=7.3e-50

Best Hits

Swiss-Prot: 76% identical to TYPA_HAEIN: GTP-binding protein TypA/BipA homolog (typA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K06207, GTP-binding protein (inferred from 97% identity to amc:MADE_01592)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (610 amino acids)

>MIT1002_03181 hypothetical protein (Alteromonas macleodii MIT1002)
MNTTDINKLRNIAIIAHVDHGKTTLVDKLLQQSGTLESRGEQEERVMDSNDIEKERGITI
LAKNTAINWNDYRINIVDTPGHADFGGEVERVMSMADSVLLLVDAQEGPMPQTRFVTQKA
FAQGLKPIVVINKIDKPGARPDWVMDQVFDLFDNLGATDEQLDFQVVYASALNGWASLDA
DTKEDDMTALFQTIVDQVSPPDADIDGAFQMQISQLDYNSYVGVIGVGRVKRGSVKPNQQ
VTVVTADGKKRNGKVGLVYGYLGLARHEVESAHAGDIIAITGLGELKISDTICDVNTVEA
LPPLTVDEPTVTMTFQVNTSPFAGKEGKYVTSRNILERLKDELVHNVALRVEEMPDPDKF
RVSGRGELHLGILIENMRREGYELAVSRPEVILKEVDGATQEPYETLTIDCEEQHQGSIM
EQLGLRKAEMTDMSPDGKGRVRIDFIIPSRGLIGFQTEFMTLTSGSGLLYHTFDHYGPYK
GGIIGKRKNGVLIANANGKALTNALFNLQERGRLFIGHGVEVYEGMVIGIHSRDNDLTVN
ALKGKQLTNVRASGTDEAQTLVPPIRMSLEQALEFIDDDELVEVTPESIRIRKKLLTENE
RKRASRAPKS