Protein Info for MIT1002_03152 in Alteromonas macleodii MIT1002

Annotation: Glycyl-glycine endopeptidase ALE-1 precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 signal peptide" amino acids 1 to 46 (46 residues), see Phobius details PF08525: OapA_N" amino acids 13 to 40 (28 residues), 21.3 bits, see alignment (E = 4.9e-08) PF04225: LysM_OapA" amino acids 80 to 155 (76 residues), 39.8 bits, see alignment E=9.5e-14 PF19425: Csd3_N2" amino acids 179 to 293 (115 residues), 63.3 bits, see alignment E=5.2e-21 PF01551: Peptidase_M23" amino acids 306 to 400 (95 residues), 99.5 bits, see alignment E=2.5e-32

Best Hits

KEGG orthology group: None (inferred from 94% identity to amc:MADE_01618)

Predicted SEED Role

"Peptidase, M23/M37 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>MIT1002_03152 Glycyl-glycine endopeptidase ALE-1 precursor (Alteromonas macleodii MIT1002)
MRKKLDASKALNLFKKLPKQHRTGLAVASLFLGGLILFPSEPVEASRHQEAHILDAGVRY
PVELHIAPSTNVFSGEEESSWQTYKVRSGDTLAKLFKRAGFTSRDVYNVTQAGELTKTLV
TLLPGDELSFKANKDGSFGELKYKLSSTETLFVRPESSDENSALTAELEKRDVDIRYNFA
QGEIHSSFWNAASDAGLTSNQIMNLAGIFGWDIDFAIEIRSGDTFNVVFEEQYIDGEFVG
YGDIVAAEFTNQGEHFSAILHEDGTYYTPEGRSMRKSFLRAPVNFRYVSSNFTKARFHPV
QKRWKAHRGTDYVAAVGTPIMAAGDGKVIKAGYDKYNGHHVFIQHGEKYTTKYLHFKKRA
VKVGDTVKQGQTVGYLGSSGMVTGAHLHYEFLVDGVHRNPRTVELPKALPIAKEERERFM
EIAAIRQEQLDNNKRIMLAMK