Protein Info for MIT1002_03087 in Alteromonas macleodii MIT1002

Annotation: Excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 849 PF17755: UvrA_DNA-bind" amino acids 159 to 268 (110 residues), 43.1 bits, see alignment E=1.2e-14

Best Hits

Predicted SEED Role

"Excinuclease ABC subunit A paralog of unknown function" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (849 amino acids)

>MIT1002_03087 Excinuclease ABC subunit A (Alteromonas macleodii MIT1002)
MHNNEGKIHVRGARVHNLKNISIDIPRNEVVVFTGVSGSGKSSLAFGTLYAEAQHRYLDS
ISPYARRLIEQVEKPDVDAIDGLPPAVGLHQRRGAPSVRSSVGSITTLSNSLRMLYSRAG
DYPKGQSIVYADGLSPNTPEGACEHCDGIGKVFDTQAHRLVPDDSLTIREGAVAAWPGAW
QGKNLVRVLLSLDIDVDIPWRELPQRTRDWILFTDEMPQLPVYRNYNLAQTRKAQQEGEP
ASYNGKFISARRHVLDTFKTSQKEKMKQRIAPFISVEACPVCRGKKLKQNALAVKVDGLD
IIEFSRLPLQQVHEKLQALRKSVNGDTSERGQVIRNITGDLIERVKPIIALGLHYLSLDR
STTSISVGELQRLRLATQLKSNLFGVVFVMDEPSSGLHPRDVEGLIRALHNITETGNSLL
VVEHNPYVIKGANWVVDVGPRAGVNGGELVYSGPVKELASTKNSLTADYVFNNKALSQRI
KCKSSGVLRLKDVSRNNVSHVDIDIPLGVMTCVTGVSGSGKSSLISQALVELVKGGLNSA
EKEGVRANETRETEETKELLTDANSLLTNDTFSHKSEPQQGLIESGLEELSRIVVVDQSP
IGRTPRSTLATYTGIFDQIRSLFASTEEAKSRGYDAGHFSFNVAKGRCSHCEGLGVVSVE
LLFMPSVYSPCTVCNGQRFNDNVLEVGYNEHSIADVLSLTVEEALSVFSGNQVITRGLKT
LMNVGLGYLTLGQSATELSGGEAQRIKLASELKRAQNANTLYVLDEPTTGLHLSDTALLM
QHLSTLVEAGNTVVMVEHNMQVAGACDYIIDMGPGAGDEGGEIVAEGRPEEVAKVQRSAT
APFLKASLA