Protein Info for MIT1002_03043 in Alteromonas macleodii MIT1002

Annotation: Hybrid peroxiredoxin hyPrx5

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 PF08534: Redoxin" amino acids 9 to 164 (156 residues), 109.1 bits, see alignment E=3.7e-35 PF00578: AhpC-TSA" amino acids 11 to 136 (126 residues), 50.8 bits, see alignment E=3.3e-17 TIGR02190: glutaredoxin-family domain" amino acids 168 to 246 (79 residues), 122.2 bits, see alignment E=3.3e-40 PF00462: Glutaredoxin" amino acids 177 to 235 (59 residues), 68.3 bits, see alignment E=1.1e-22 PF13417: GST_N_3" amino acids 181 to 241 (61 residues), 32.7 bits, see alignment E=1.6e-11

Best Hits

Swiss-Prot: 70% identical to PRX5_HAEIN: Hybrid peroxiredoxin hyPrx5 (PGdx) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 94% identity to amc:MADE_03279)

Predicted SEED Role

"Peroxiredoxin family protein/glutaredoxin"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (246 amino acids)

>MIT1002_03043 Hybrid peroxiredoxin hyPrx5 (Alteromonas macleodii MIT1002)
MSESRFTSKEGQKVPSVSFPCREGETWVTKTTDELFSGKNVVVFSLPGAFTPTCSSTHLP
RYNALAKKFAKHGIDEIVCVSVNDTFVMNAWAADQEAANITVIPDGNGEFTDGMGMLVDK
ADLGFGKRSWRYSMLVKDGVVDKMFIEPDVAGDPFEVSDADTMLAYIAPEEQTNAPVSII
TKPGCPFCAKAKKLLDEKGYEYEEIVLGKDASLTSLTAISGRETVPQVFIGGKHIGGSDD
LEVYFS