Protein Info for MIT1002_03021 in Alteromonas macleodii MIT1002

Annotation: Cell division protein FtsA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 TIGR01174: cell division protein FtsA" amino acids 9 to 378 (370 residues), 510.3 bits, see alignment E=1.6e-157 PF02491: SHS2_FTSA" amino acids 85 to 162 (78 residues), 110.4 bits, see alignment E=1.1e-35 PF06723: MreB_Mbl" amino acids 204 to 353 (150 residues), 45.1 bits, see alignment E=1.6e-15 PF14450: FtsA" amino acids 207 to 374 (168 residues), 130 bits, see alignment E=1.7e-41

Best Hits

Swiss-Prot: 58% identical to FTSA_SHIFL: Cell division protein FtsA (ftsA) from Shigella flexneri

KEGG orthology group: K03590, cell division protein FtsA (inferred from 97% identity to alt:ambt_02225)

Predicted SEED Role

"Cell division protein FtsA" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (409 amino acids)

>MIT1002_03021 Cell division protein FtsA (Alteromonas macleodii MIT1002)
MSKPAERNLIVGLDIGTSQVKAVVGELLEDDQISIVGVGTHASKGMDKGGVNDLNLVVKS
VQRAVNEMELMADCRVSSVFMSISGRHVKCQNENGMVPINNQEVTQEDVDNVIHAARSVP
IAAERRLLHVLPQEFTIDVQEGIKNPIGMSGVRMEADAHIITCADDMAKNMVKCVERCEL
NADQLIFSALASSYAVLTDDERELGVCVVDIGGGTMDMVIYTDGAIRHTAVIPVAGNQIT
SDIAKIFRTPISNAEEIKVNYACALKDMVSMEDSIEVPSVGGRPARVMSRHTLAEVIEPR
YQELFELVHDEIRASGLEEQIAAGLVLTGGTAKMEGAVEFAEELFQMPVRVGKPINVKGL
SEYVDDAGFATVVGLLQYGKVQSDNKKSSTQKTGESLFHRVQSWFKGEF