Protein Info for MIT1002_02489 in Alteromonas macleodii MIT1002

Annotation: Deoxycytidine triphosphate deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 197 TIGR02274: deoxycytidine triphosphate deaminase" amino acids 2 to 190 (189 residues), 225.8 bits, see alignment E=1.5e-71 PF06559: DCD_N" amino acids 3 to 139 (137 residues), 38.1 bits, see alignment E=2.2e-13 PF22769: DCD" amino acids 4 to 161 (158 residues), 141.3 bits, see alignment E=4.3e-45 PF00692: dUTPase" amino acids 81 to 184 (104 residues), 24.4 bits, see alignment E=3.2e-09

Best Hits

Swiss-Prot: 99% identical to DCD_ALTMD: dCTP deaminase (dcd) from Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

KEGG orthology group: K01494, dCTP deaminase [EC: 3.5.4.13] (inferred from 99% identity to amc:MADE_01987)

MetaCyc: 74% identical to dCTP deaminase (Escherichia coli K-12 substr. MG1655)
dCTP deaminase. [EC: 3.5.4.13]

Predicted SEED Role

"Deoxycytidine triphosphate deaminase (EC 3.5.4.13)" (EC 3.5.4.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (197 amino acids)

>MIT1002_02489 Deoxycytidine triphosphate deaminase (Alteromonas macleodii MIT1002)
MRLCDRDIYQHLQDGKIKIDPTPSYDQISGVTVDIRLGNKFRVFEDHQAPFIDLSGPKAQ
VQEALDHVMSDEIELEEGKAFFLHPGELALAITHESVTLPDNIVGWLDGRSSLARLGLMV
HVTAHRIDPGWSGNIVLEFYNSGKLPLALRPKMKIGALSFEVLSAPAEKPYNARVDAKYK
GQAGAVASRISSDDESK