Protein Info for MIT1002_02488 in Alteromonas macleodii MIT1002

Annotation: Na(+)/dicarboxylate symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 478 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 46 to 62 (17 residues), see Phobius details amino acids 67 to 85 (19 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 120 to 142 (23 residues), see Phobius details amino acids 149 to 171 (23 residues), see Phobius details amino acids 178 to 198 (21 residues), see Phobius details amino acids 225 to 243 (19 residues), see Phobius details amino acids 266 to 283 (18 residues), see Phobius details amino acids 285 to 307 (23 residues), see Phobius details amino acids 335 to 356 (22 residues), see Phobius details amino acids 365 to 388 (24 residues), see Phobius details amino acids 395 to 413 (19 residues), see Phobius details amino acids 419 to 439 (21 residues), see Phobius details amino acids 458 to 477 (20 residues), see Phobius details PF00939: Na_sulph_symp" amino acids 47 to 470 (424 residues), 181.1 bits, see alignment E=4.2e-57 TIGR00785: transporter, divalent anion:Na+ symporter (DASS) family" amino acids 50 to 475 (426 residues), 248.7 bits, see alignment E=5.1e-78 PF03600: CitMHS" amino acids 58 to 414 (357 residues), 185.7 bits, see alignment E=1.3e-58

Best Hits

KEGG orthology group: K14445, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 (inferred from 92% identity to amc:MADE_01988)

Predicted SEED Role

"anion transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (478 amino acids)

>MIT1002_02488 Na(+)/dicarboxylate symporter (Alteromonas macleodii MIT1002)
MHTNSEPSSETLQRKPTRKNSIILFAFIASVLCGLGLWAIDQPSEIIFTAAITLFVAVLW
VTEALPIPATSLLPFALFPLFGVLSHSEAASALGSHVIILLMAAFMLSKGLERANLHKRF
AIYMLRITGSGSPLKLVLGFMLTTAVLSMWISNTATILMMLPMAIAIINAVDNPRFGVAL
ILGIAYSASLGGVGTPIGTPPNIIFMSVYEETQGIEYSFIDWMKTGVPIVILGVPIMALW
LARGIKQVGNIDLPVPGTWTKAEKRVLAIFGTVALAWIFRPFWTAWIGISTISDSTIAVA
GVAAMFFTNSGNDNGEVDEKGNNDKLLDWKTANDIPWGMLLLFAGGICIAKAFMSSGLSV
LMGTWLTGLSTLPVLLLVLGICLFVTFLTEITSNTATSTLLMPILAAAGMAVGVDPKLLM
IPAAISASCAFMLPVATAPNAIAYSTEKFDIKTMAREGVVLNVLVALVVTGVCYVTLA