Protein Info for MIT1002_02428 in Alteromonas macleodii MIT1002

Annotation: Neu5Ac permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 transmembrane" amino acids 7 to 35 (29 residues), see Phobius details amino acids 54 to 74 (21 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 139 to 166 (28 residues), see Phobius details amino acids 172 to 198 (27 residues), see Phobius details amino acids 219 to 239 (21 residues), see Phobius details amino acids 245 to 262 (18 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 317 to 335 (19 residues), see Phobius details amino acids 340 to 358 (19 residues), see Phobius details amino acids 364 to 390 (27 residues), see Phobius details amino acids 402 to 421 (20 residues), see Phobius details PF06808: DctM" amino acids 9 to 420 (412 residues), 421.8 bits, see alignment E=1.4e-130 TIGR00786: TRAP transporter, DctM subunit" amino acids 20 to 426 (407 residues), 434.4 bits, see alignment E=1.9e-134

Best Hits

Swiss-Prot: 49% identical to YGIK_SALTY: Uncharacterized protein YgiK (ygiK) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 68% identity to ttu:TERTU_0893)

Predicted SEED Role

"TRAP-type C4-dicarboxylate transport system, large permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>MIT1002_02428 Neu5Ac permease (Alteromonas macleodii MIT1002)
MELTGIILVVTFFVLLLLNVPISISIGVATLLAMVMSMDIAPATITIAQRMAGGLNSFAL
LAIPFFVLSGLIMGRGGIAKRLIECAMALIGALPGGLALVNVVSCMLFGAISGSAVATTS
AIGSFMLPEMKKAGYEPNFSAAVTAAASTTGMLIPPSNILIVYAIASGGVSIAALFMAGY
IPGIMVGLALMLVCFIYAKMKGYPLSPRLPIKVVVEKTIAALPSLFLIFLVIGGIVGGVF
TATEAGAIAVVYSLLLAVVFYKEVDAKALPDIFLKAAETTAIVMLLIAASTAMSWLLSFE
NIPQTLSNALLSISDNPLLILLLINLLLIVVGAFLDMTPAVLIFTPIFLPVALELGMSEL
QFGIMLVLNLSIGLCSPPVGAVLFITCAIAKTKLENIIRPLIPLYVAMFVVLMLVTYVAW
FSEALPRALGF