Protein Info for MIT1002_02167 in Alteromonas macleodii MIT1002

Annotation: Modulator of FtsH protease YccA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 transmembrane" amino acids 24 to 45 (22 residues), see Phobius details amino acids 51 to 67 (17 residues), see Phobius details amino acids 77 to 99 (23 residues), see Phobius details amino acids 105 to 126 (22 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 161 to 179 (19 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details PF01027: Bax1-I" amino acids 19 to 214 (196 residues), 176.9 bits, see alignment E=2.4e-56

Best Hits

Swiss-Prot: 55% identical to Y1358_VIBCH: Uncharacterized membrane protein VC_1358 (VC_1358) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K06890, (no description) (inferred from 96% identity to alt:ambt_08420)

Predicted SEED Role

"Putative TEGT family carrier/transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (221 amino acids)

>MIT1002_02167 Modulator of FtsH protease YccA (Alteromonas macleodii MIT1002)
MDQRSMYSSASQPSVLQTNKVLRNTYMLLAMTLAFSAVCAGIAMAVGISPMMSLVMTIGA
FITLFVVQKKADSASGIYWVFAFTGLMGASLGYTLNFYLGVAGPGLIMEALGATALVFFA
LSGYALTTKKDFSFMGGFLVVGLVVVLVAAIANIFFAVPAVSLAISAAIVFIMSGFILFD
TSRIIHGGETNYIRATVSLYLNIYNLFTSILHLLGAFGGDD